Uncategorized
AUSTIN, Texas, Nov. 9, 2016 — ASPiRA LABS, a Vermillion company (NASDAQ: VRML), today announced the inclusion of the OVA1 /”Multivariate Index Assay” in The American College of Obstetricians and Gynecologists (ACOG) Practice Bulletin Number 174, dated November 2016. This bulletin outlines ACOG’s “new” clinical management guidelines for adnexal mass management.
These new clinical management guidelines replace the July 2007 version, Practice Bulletin 83. According to the ACOG website, “Practice Bulletins summarize current information on techniques and clinical management issues for the practice of obstetrics and gynecology. Practice Bulletins are evidence-based documents, and recommendations are based on the evidence.” This is also the only clinical management tool used for Adnexal Masses. Guidelines DO NOT exist for Adnexal Masses, only Practice Bulletins. Please note Guidelines do exist however for Ovarian Cancer management.
The new guidelines now recommend that all obstetricians and gynecologists, in evaluating women with adnexal masses when the mass does not fulfill Level A criteria of a low risk transvaginal ultrasound (TVUS), should proceed with Level B clinical guidelines. Level B guidelines state that the physician should use risk assessment tools such as OVA1 (“Multivariate Index Assay”) as listed in the bulletin. Based on this, OVA1 has now achieved parity with CA125 as a Level B recommendation for the management of adnexal masses, but it is the only recommended Level B tool with FDA clearance for use in assessing ovarian cancer risk in adnexal masses. CA125 does not have FDA clearance for use in assessing ovarian cancer risk in adnexal masses. The new guidelines suggest that if an elevated risk of malignancy does exist, then the provider must consult with or refer to a gynecologic oncologist. This is in direct relationship to the OVA1 FDA cleared label.
“These new guidelines will raise overall physician awareness of the importance of using a proactive risk assessment such as OVA1 when the TVUS does not meet Level A criteria,” stated Valerie Palmieri, President and CEO of Vermillion, Inc. “Having OVA1 as a Level B recommendation is a milestone event for saving women and properly assessing the risk of ovarian cancer from the onset of disease.”
About Vermillion
Vermillion, Inc. is dedicated to the discovery, development and commercialization of novel high-value diagnostic and bio-analytical solutions that help physicians diagnose, treat and improve gynecologic health outcomes for women. Vermillion, along with its prestigious scientific collaborators, discovers, develops, and delivers innovative diagnostic and technology tools that help women with debilitating diseases. The company’s initial in vitro diagnostic test, OVA1®, was the first FDA-cleared, protein-based In Vitro Diagnostic Multivariate Index Assay, and represented a new class of software-based liquid biopsy in vitro diagnostics. In March 2016, Vermillion received FDA clearance for Overa™, a second generation OVA1 test with significantly improved specificity and ease of use. For additional information, including published clinical trials, visit www.vermillion.com.
About OVA1®
- OVA1 is a proprietary FDA-cleared blood test designed to help physicians assess the risk of ovarian cancer prior to surgery, facilitating more effective referral of high risk patients to a specialist (gynecologic oncologist) for surgical treatment.
- The OvaCalc® proprietary algorithm combines five biomarker results into a single numerical “risk score” that stratifies patients into “higher risk” and “lower risk” when combined with clinical assessment.
- In two pivotal clinical trials, OVA1 plus clinical impression detected 96% of all malignancies vs. 75% for clinical impression alone. As a result, false negatives were reduced from 25% for clinical impression alone, to 4% with OVA1 plus clinical impression, a reduction of 83%.
- In a study focused on early-stage ovarian cancer detection, 31% of cases were missed by clinical impression alone. This was reduced to 5% when OVA1 was added to clinical impression, a reduction of 85%.
- OVA1 has shown clinical utility in increasing the rate of referrals of malignant adnexal masses to gynecologic oncologists. The increased involvement of specialists may lead to increased National Comprehensive Cancer Network-adherent cancer care, which is associated with improved cancer outcomes, including overall survival. In a study focused on specialist involvement in ovarian cancer treatment, 94% of patients with an elevated-risk OVA1 result who had primary ovarian malignancies were appropriately referred to a gynecologic oncologist.
Investor Relations Contact:
Michael Wood
LifeSci Advisors LLC
Tel 1-646-597-6983
mwood@lifesciadvisors.com
Farmer Bros. Sets the Record Straight on Corporate Relocation, Capital Allocation and Independent Board Members The Waite Group is Misleading Farmer Bros. Stockholders and Offering No Plan to Create Value The Board Urges Stockholders to Protect Their Investment by Voting “FOR” Each of Farmer Bros.’ Highly Qualified Director Nominees on the GOLD Proxy Card
FT. WORTH, Texas, Nov. 8, 2016 — Farmer Bros. Co. (NASDAQ: FARM, the “Company” or “Farmer Bros.”) today mailed a letter to its stockholders in connection with the Company’s upcoming 2016 Annual Meeting of Stockholders to be held on December 8, 2016.
Highlights from the letter include:
- Under the direction of the current Farmer Bros. Board of Directors as well as Michael H. Keown, President and CEO, the Company continues to successfully execute a turnaround plan that is improving the Company’s operational and financial results, and creating substantial value for all stockholders.
- Meanwhile, the Waite Group overlooks the substantial benefits of Farmer Bros.’ corporate relocation plan and other operating initiatives that represent the Farmer Bros. current Board’s and management team’s focus on continuous improvement – despite the fact that Jonathan Michael Waite, a member of the Waite Group and son of Carol Farmer Waite, was a proponent of the relocation plan – and fails to acknowledge the thorough review and analysis undertaken by the Board and management prior to announcing the relocation.
- The Waite Group mischaracterizes Farmer Bros.’ capital allocation decisions, which have been organized under the Company’s current Board and management to maximize efficiency and drive stockholder value.
- Contrary to misleading claims by the Waite Group, the three most recently added independent directors were identified and selected through a rigorous process under the direction of the Nominating Committee and initially introduced to Farmer Bros., and strongly supported by, an independent third-party search firm that was recommended by Jeanne Farmer Grossman.
- Your Board of Directors strongly believes the Waite Group has nominated a slate of unqualified and inexperienced director candidates and failed to articulate any plan for Farmer Bros.’ future, let alone one that would create stockholder value, to warrant Board representation in place of the Company’s three highly qualified and proven director nominees.
- The future of Farmer Bros. and your investment are at risk because the election of the Waite Group’s three nominees, combined with Farmer family representatives already on the Board, would effectively lead to a change of control of the Board and Farmer Bros.
The full text of the letter being mailed to stockholders follows:
VOTE THE ENCLOSED GOLD PROXY CARD TODAY
“FOR” ALL THREE OF FARMER BROS.’ HIGHLY QUALIFIED DIRECTOR NOMINEES
November 8, 2016
Dear Farmer Bros. Co. Stockholder:
Under the leadership and direction of the current Board of Directors (the “Board”) of Farmer Bros. Co. (the “Company” or “Farmer Bros.”) as well as Michael H. Keown, President and Chief Executive Officer, Farmer Bros. continues to successfully execute a turnaround plan that is creating substantial value for all stockholders.
The Waite Group is seeking to replace three Farmer Bros. directors with its own nominees at the upcoming 2016 Annual Meeting of Stockholders on December 8, 2016.
Stockholders are faced with a critical choice: reelect your Board’s three highly qualified nominees, each of whom brings a vast amount of industry expertise, a deep understanding of the business and has helped oversee the Company’s successful turnaround strategy – or the Waite Group’s candidates, who lack the skills and experience necessary to deliver strong financial results and superior stockholder value, would add no value to the Company’s Board, would replace a successful management team and would derail the Company’s proven turnaround strategy.
The answer is clear: protect the value of your Farmer Bros. investment by voting the enclosed GOLD proxy card today for the Board’s nominees – Michael H. Keown, Charles F. Marcy and Christopher P. Mottern. Voting any card other than GOLD may cause Farmer Bros. to lose three highly qualified board members.
LET’S SET THE RECORD STRAIGHT
THE WAITE GROUP IGNORES THE FACT THAT FARMER BROS. CONTINUES
TO EXECUTE A SUCCESSFUL TURNAROUND STRATEGY THAT HAS CREATED
SUBSTANTIAL VALUE FOR ALL STOCKHOLDERS
Your Board and management team are continuing to execute a successful turnaround strategy that is improving the Company’s operational and financial results. Further, the Waite Group has misled stockholders by selectively focusing on one metric while ignoring the fact that from fiscal 2012 through fiscal 2016, Farmer Bros.:
- Increased green coffee pounds sold and processed by over 40%, or achieved compound annual growth of approximately 9%;
- Expanded gross margin by 493 basis points while the industry peer group’s gross margin declined by 380 basis points; and
- Reversed Farmer Bros.’ GAAP net loss of $27 million in fiscal 2012 to GAAP net income of $90 million in fiscal 2016.i
Since March 13, 2012, when the Board appointed Mr. Keown as President and CEO, Farmer Bros.’ stock price has appreciated over 225%, representing strong value creation of over $400 million for stockholders. In that time-frame, the Company’s total stockholder return outperformed the Russell 2000 Index as well as the Food Processing Index. Additionally, the Company’s total stockholder return has consistently outperformed both the S&P 500 and its peer set over almost any timeframe since 2012.ii
In contrast, during fiscal 2005 to fiscal 2009 when Carol Farmer Waite served as a member of the Company’s Board, Farmer Bros. had approximately $35 million of cumulative net losses. Further, Farmer Bros.’ stock price declined 43% during the time that Ms. Waite and/or John Samore, one of the Waite Group’s nominees, served on the Board. iii
THE WAITE GROUP FAILS TO ACKNOWLEDGE THE THOROUGH ANALYSIS UNDERTAKEN OR THE SUBSTANTIAL BENEFITS OF FARMER BROS.’ CORPORATE RELOCATION
Contrary to claims made by the Waite Group, Farmer Bros.’ decision to relocate its facilities and headquarters from an aging and inefficient facility in Torrance, California, to a new, state-of-the-art facility in Northlake, Texas followed a thorough, methodical and thoughtful 18+-month review of the Company’s operations as well as the potential manufacturing, distribution and supply chain savings that are expected to result from the move.
The evaluation began in earnest in August 2013 and deliberations and considerations were made until the final decision was announced 18 months later. Similarly, the Waite Group chooses to ignore the benefits resulting from the new facility’s central location as it relates to the Company’s nationwide customer base, the increased manufacturing capacity to support future growth that the new facility offers, and the potential to introduce new efficiencies and help control supply chain costs.
As the Company has previously stated, the corporate relocation is expected to produce annual cost savings of approximately $18 million to $20 million. As of year-end fiscal 2016, the Company had already achieved more than half of the expected annual savings rate, with the majority of the savings flowing through the 220 basis point improvement in gross margin seen in fiscal 2016.
| Notably, Jonathan Michael Waite, the son of Carol Farmer Waite and a member of the Waite Group, has been an ongoing proponent of the relocation, despite the fact that he is part of a group claiming the decision was “hastily made” and not “properly analyzed.” Mr. Waite served as a member of the employee team that planned and analyzed the move, was part of a relocation team that presented to the Board as part of the Board’s review and analysis, and participated in field visits to help select the new facility site. |
THE WAITE GROUP MISLEADS STOCKHOLDERS BY MISCHARACTERIZING
FARMER BROS.’ CAPITAL ALLOCATION DECISIONS
Since fiscal 2012, under the direction of the current Board and management team, the Company’s capital allocation policy seeks to maximize efficiency and drive stockholder value. In trying to bolster its campaign, the Waite Group attempts to mislead stockholders with false assertions:
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Questioned the Company’s decision to transition to Third-Party Logistics (“3PL”) following investments in mechanical upgrades and a rebranding of Farmer Bros.’ fleet operation. |
The transition to 3PL followed careful analysis and is expected to produce annualized cost savings of approximately $2.1 million of the estimated $18-$20 million in total cost savings. Under the terms of the agreement with the 3PL provider, Farmer Bros. is compensated for the use of the fleet as the 3PL provider continues to use the rebranded trucks in transporting Farmer Bros. goods. Additionally, a “rebranding” of Farmer Bros.’ fleet was simply placement of new logo panels on trucks aligning with a broader logo refresh to eliminate an outdated slogan and industry award reference, while mechanical upgrades were to improve fuel efficiency. |
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Overstated an immaterial investment in the Company’s e-commerce capabilities. |
Like any responsible consumer-branded company operating in today’s competitive business environment, Farmer Bros. has made certain strategic investments in its e-commerce business to meet the demands of its customers and consumers and help strengthen the Farmer Bros. brand recognition. The Company’s e-commerce initiative consisted of upgrading Farmer Bros.’ ERP system and optimizing search engine capability to provide a platform allowing customers to order products online. However, the investment in e-commerce was a relatively immaterial amount, less than $85,000. |
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Mischaracterized Farmer Bros. energy and sustainability initiatives at the Torrance, CA plant. |
To avoid a penalty from its utility company, the Company undertook an initiative to flatten energy demand spikes at its Torrance facility, improving its average power factor (power system’s capacity available for productive work) from approximately 75% to above the utility company’s required 80%. |
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Questioned necessary investments in production-line equipment in Torrance and Houston. |
To bring its air quality into compliance with California State standards, avoid costly fines and risk potential reduced production capacity from the shut-down of its roasters, Farmer Bros. invested approximately $1.2 million commencing in 2013 to upgrade its roasters and also purchased additional roasters that were not installed in Torrance but can be utilized in other facilities. Investments in Houston of approximately $1.7 million were made to upgrade older, inefficient production lines, to balance volume, and to add a roaster to meet increased capacity requirements. Useable equipment from Torrance was relocated to Houston and the new Northlake, Texas facility to reduce capital expenditures in both facilities. Investments in equipment for the Houston facility, and improvements in efficiency, quality, and safety that accompanied this equipment, are a significant contributor to gross margin improvements that followed the exit of production from Torrance. |
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FARMER BROS.’ BOARD IS LED BY INDEPENDENT, OUTSIDE DIRECTORS WHO ARE EXPERT, ACTIVE AND FOCUSED ON THE BEST INTERESTS OF ALL STOCKHOLDERS
The Company’s current Board offers superior industry and operational expertise that is driving the Company’s turnaround plan, effective independent leadership with Randy E. Clark having been appointed as Independent Chairman in 2015 and fresh perspectives with five of the seven Board members added in the past five years.
Contrary to false claims by the Waite Group that Mr. Keown hand-picked a number of directors, the three most recently added independent directors were sourced and selected through a rigorous process driven by the Nominating Committee, with the support of an independent, third-party search firm that was recommended by Jeanne Farmer Grossman, Carol Farmer Waite’s sister.
In 2011, prior to Mr. Keown joining the Company, Mr. Clark was introduced to Jeanne Farmer Grossman by a recruiter with Leadership Capital Partners, LLC, a leading independent search consultant. In 2012, Ms. Grossman recommended Mr. Clark to the then-Chairman of the Board, Guenter W. Berger, who subsequently brought Mr. Clark to the attention of the Nominating Committee. Following the recommendation of the Nominating Committee, the Board concluded that Mr. Clark was a qualified candidate based on his extensive experience in food and food service businesses, as well as his accounting and financial expertise.
Similarly, Messrs. Marcy and Mottern were brought to the attention of the Nominating Committee and the Board by Leadership Capital Partners, LLC in 2013. The Board conducted a lengthy interview process in which eight candidates were considered and vetted by the full Board. The Board concluded that Mr. Marcy was a qualified candidate due to over four decades of experience as a senior executive, or advisor, of companies in the food industry as well as his corporate governance, public company board and executive compensation experience; and that Mr. Mottern was a qualified candidate due to his over three decades of senior executive experience in the food and beverage industry, including as former President and CEO and member of the Board of Directors of Peet’s Coffee & Tea, Inc., as well as his financial and accounting experience which would allow him to serve on the Company’s audit committee as a financial expert under applicable rules of the SEC.
Notably, during 2013, when Messrs. Marcy and Mottern were elected to the Board of Directors, the Nominating Committee included members who were appointed by the previous Farmer family regime or were former long-term employees of Farmer Bros.
WE BELIEVE THAT ELECTING THE WAITE GROUP’S NOMINEES WILL GIVE EFFECTIVE CONTROL OF THE BOARD AND COMPANY TO SELECT MEMBERS OF THE FARMER FAMILY WHOSE INTERESTS ARE NOT ALIGNED WITH ALL STOCKHOLDERS
The Waite Group again attempts to mislead stockholders by claiming that the Board lacks significant stockholder representation, and that the election of its nominees will constitute a minority on the Board. The reality is that three of the seven directors currently on the Board are either a member of the Farmer family or serve on the Board as a result of Farmer family actions or requests.
- The Farmer family is already represented on the board by Jeanne Farmer Grossman, the sister of Carol Farmer Waite and the late Roy Edward Farmer, and the daughter of the late Roy F. Farmer.
- Mr. Berger, Chairman Emeritus, has served on the Board since 1980, when he was appointed by the controlling members of the Farmer family, and was an employee of Farmer Bros. for more than 47 years.
- Hamideh Assadi, a former manager in the Company’s tax department, was appointed to the Board in 2011 upon the recommendation of Richard F. Farmer, Ph.D.
Ms. Assadi has informed the Board that she would resign if Mr. Samore is elected based on her prior negative experiences with Mr. Samore. Should the Waite Group’s three nominees be elected and Ms. Assadi resign without her seat being filled, the Waite Group, together with current Farmer-family appointees and family members, would hold five of six seats on a reconstituted Board. This would effectively change control of the Board and provide the Waite Group with the power to replace Mr. Keown and potentially other members of senior management.
THE FUTURE OF YOUR INVESTMENT DEPENDS ON YOUR VOTE
The future of Farmer Bros. and your investment depend on the Company continuing to successfully execute its proven turnaround plan that is expanding the Company’s customer base, improving operational performance, reducing costs through corporate relocation initiatives and creating substantial value for all stockholders. We need a Board comprised of outside and truly independent directors who are focused on the interest of all stockholders and who bring the right combination of critical food and beverage industry expertise, C-level executive leadership experience and operational and financial skills. The current Board, including the Board’s three nominees, and management team have driven stockholder value creation that is best-in-class and above Farmer Bros.’ peers and the broader market.
It is clear that the Waite Group has no plan for Farmer Bros.’ future other than to replace the current successful management team. Further, your Board strongly believes that the Waite Group’s nominees lack the qualifications and experience necessary to deliver strong financial results and superior stockholder value and would add no value to the Board. Electing the Waite Group nominees effectively puts control of the Board in the Waite Group’s hands, puts the Company’s leadership at risk and would derail the Company’s proven turnaround plan.
In contrast, we are confident that our three nominees – Michael H. Keown, Charles F. Marcy and Christopher P. Mottern – have exactly the right skills and expertise your Company needs to continue to drive growth and deliver value for all stockholders and have a proven track record of driving stockholder value. Please protect the future of your investment by voting the GOLD proxy card TODAY.
| We encourage you to vote today by signing and dating the enclosed GOLD proxy card and returning it in the postage-paid envelope provided, or by voting over the Internet or by telephone. |
On behalf of your Board of Directors, we thank you for your continued support.
Sincerely,
Randy E. Clark
Chairman of the Board
| Your Vote Is Important, No Matter How Many or How Few Shares You Own
If you have any questions or require any assistance with respect to voting your shares, please contact the Company’s proxy solicitor at the contact listed below:
M O R R O W
S O D A L I
470 West Avenue
Stamford, Connecticut 06902
Stockholders Call Toll Free: (800) 662-5200
Banks and Brokers Call Collect: (203) 658-9400
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About Farmer Bros. Co.
Founded in 1912, Farmer Bros. Co. is a national coffee roaster, wholesaler and distributor of coffee, tea and culinary products. The Company’s product lines include organic, Direct Trade and sustainably-produced coffee. With a robust line of coffee, hot and iced teas, cappuccino mixes, spices, and baking/biscuit mixes, the Company delivers extensive beverage planning services and culinary products to its U.S. based customers. The Company is a direct distributor of coffee to restaurants, hotels, casinos, offices, quick service restaurants, convenience stores, healthcare facilities and other foodservice providers, as well as private brand retailers.
Headquartered in Fort Worth, Texas, Farmer Bros. Co. generated net sales of over $500 million in fiscal 2016 and has approximately 1,600 employees nationwide. The Company’s portfolio features a wide range of coffees including Farmer Brothers®, Artisan Collection by Farmer Brothers™, Metropolitan™, Superior®, Cain’s™ and McGarvey®.
Forward-looking Statements
Certain statements in this communication constitute “forward-looking statements.” When used in this communication, the words “will,” “expects,” “anticipates,” “estimates” and “believes,” and similar expressions and statements that are made in the future tense or refer to future events or developments, are intended to identify such forward-looking statements. Such forward-looking statements are subject to risks, uncertainties and other factors that could cause the actual results, performance or achievements to be materially different from any future results, performance or achievements expressed or implied by such forward-looking statements. Forward-looking statements include, but are not limited to, statements regarding the expected cost savings relating to the Company’s corporate relocation. These statements are based on management’s current expectations, assumptions, estimates and observations of future events and include any statements that do not directly relate to any historical or current fact; actual results may differ materially due in part to the risk factors set forth in our most recent annual, periodic and current reports filed with the SEC.
Undue reliance should not be placed on the forward-looking statements in this communication, which are based on information available to the Company on the date hereof, and the Company assumes no obligation to update such statements.
Important Additional Information and Where to Find It
Farmer Bros. Co. has filed a definitive proxy statement and accompanying proxy card with the SEC in connection with the solicitation of proxies from the Company’s stockholders in connection with the matters to be considered at the Company’s 2016 Annual Meeting. Additional information regarding the identity of participants, and their direct or indirect interests, by security holdings or otherwise, is set forth in the Company’s definitive proxy statement, including the schedules and appendices thereto.
THE COMPANY URGES ITS INVESTORS AND STOCKHOLDERS TO READ CAREFULLY AND IN THEIR ENTIRETY THE DEFINITIVE PROXY STATEMENT (INCLUDING ANY SUPPLEMENTS OR AMENDMENTS), THE ACCOMPANYING PROXY CARD AND ANY OTHER DOCUMENTS THAT THE COMPANY MAY FILE WITH THE SEC WHEN THEY BECOME AVAILABLE BECAUSE THEY WILL CONTAIN IMPORTANT INFORMATION.
Farmer Bros. Co., certain of its directors and certain of its executive officers may be deemed to be participants in the solicitation of proxies from the Company’s stockholders in connection with the matters to be considered at the Company’s 2016 Annual Meeting. Information regarding the names of the Company’s directors and executive officers and their respective interests in the Company by security holdings or otherwise is set forth in the Company’s definitive proxy statement for its 2016 Annual Meeting. To the extent holdings of the Company’s securities have changed since the amounts set forth in the Company’s definitive proxy statement for the 2016 Annual Meeting, such changes have been reflected on Initial Statements of Beneficial Ownership on Form 3, Statements of Change in Ownership on Form 4 or Annual Statements of Changes in Beneficial Ownership of Securities on Form 5 filed with the SEC. These documents are available free of charge at the SEC’s website at www.sec.gov.
Copies of the definitive proxy statement (including any supplements or amendments), the accompanying proxy card, and any other documents filed by the Company with the SEC will be available free of charge at the SEC’s website at www.sec.gov. Copies will also be available free of charge at the Investor Relations section of the Company’s website at www.farmerbros.com.
Additional Information
INVESTOR CONTACT:
Isaac N. Johnston, Jr.
(682) 549-6663
Tom Ball / Mike Verrechia
Morrow Sodali
(203) 658-9400
MEDIA CONTACT:
Kelly Sullivan / Ed Trissel / Leigh Parrish
Joele Frank, Wilkinson Brimmer Katcher
(212) 355-4449
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i The 2016 fiscal year GAAP net income included non-cash income tax benefit of $80.3 million from the release of valuation allowance on deferred tax assets.
ii Stock price appreciation, stockholder value and total stockholder return from 03/13/2012 through 09/28/2016.
iii Stock price decline from 04/30/2003 through 12/10/2009.
– FDA Feedback Provides Clear Guidance for ZTLido™ NDA Resubmission – Itochu Corporation of Japan Partners with Sorrento on Scilex Ownership
SAN DIEGO, Nov. 8, 2016 — Sorrento Therapeutics, Inc. (NASDAQ: SRNE; “Sorrento”) and Scilex Pharmaceuticals Inc. (“SCILEX”) announced today the closing of a transaction by which Sorrento acquired a majority of SCILEX. Sorrento acquired approximately 72% of the outstanding common stock of SCILEX for a net purchase price of up to approximately $47.6 million, payable in a combination of cash and shares of Sorrento common stock. Further, the U.S. Food & Drug Administration (“FDA”) recently provided clear feedback related to the resubmission of the new drug application (“NDA”) for SCILEX’s lead product candidate, ZTlido™ (lidocaine patch 1.8%), a branded lidocaine patch formulation being developed for the treatment of postherpetic neuralgia, the chronic pain that sometimes develops with shingles.
As previously announced by Sorrento on August 8, 2016, Scintilla Pharmaceuticals, Inc., a subsidiary of Sorrento (“Scintilla”), and SCILEX entered into a binding term sheet setting forth the terms and conditions by which Scintilla would purchase all of the issued and outstanding equity of SCILEX. Scintilla and SCILEX agreed to terminate the binding term sheet on November 8, 2016. Scintilla remains committed to combining its lead program, resiniferatoxin (“RTX”), for the treatment of intractable cancer pain, with the products of Semnur Pharmaceuticals, Inc., for which a separate previously announced binding term sheet and acquisition process is moving forward towards closure prior to the end of 2016.
The maximum consideration payable by Sorrento for the acquisition of approximately 72% of the outstanding capital stock of SCILEX is approximately $47.6 million. Of this maximum consideration, 10% was paid by Sorrento at closing in Sorrento common stock (for an aggregate issuance of 752,481 shares of Sorrento common stock based on a $6.33 per share price), 10% will be paid in Sorrento common stock upon the resubmission of the NDA for the ZTlido™ product for the treatment of postherpetic neuralgia with the FDA, and the remaining 80% will be paid in either cash or Sorrento common stock or in a combination of cash and Sorrento common stock upon FDA approval of the NDA. The number of shares issuable upon the resubmission of the NDA will be determined using the market price per share of Sorrento common stock on the date of such resubmission and the number of shares issuable upon FDA approval of the NDA will be determined using the market price per share of Sorrento common stock on the date of such approval; however, in either case the calculation of the number of shares issuable will not use a price per share that is less than $6.33 or greater than $25.32. ITOCHU CHEMICAL FRONTIER Corporation (“ICF”), a member of ITOCHU Corporation (ITOCHU), a Fortune Global 500 company and one of the three leading sogo shosha (general trading companies) in Japan, is continuing as an approximate 23% owner of SCILEX.
SCILEX filed the initial NDA for ZTlido™ in July 2015. The SCILEX team met with the FDA in late August 2016 and, based on that feedback has a clear plan for NDA re-submission with a potential FDA action date in the second half of 2017. In addition to ZTlido™, the SCILEX pipeline includes line extensions of ZTlido™ as well as the exploration of other novel patch technologies.
“The acquisition of a majority of SCILEX significantly enhances Sorrento’s late stage pipeline and footprint in the treatment of acute and chronic inflammation and pain. We are very pleased with FDA’s recent guidance relating to SCILEX’s lead product ZTlido™ and believe that we have been provided a clear path to near term resubmission,” said Dr. Henry Ji, President and CEO of Sorrento. Dr. Ji added, “Through this acquisition, we have also fostered a strong relationship with Itochu Corporation, a leading Japanese company with $45 billion in annual revenues. We look forward to working together with our new business partner to drive the future of this franchise.”
“We believe strongly in the value of SCILEX’s cutting edge technology and the commercial potential for ZTlido™,” stated Toshinari Hidekuma, Itochu Chemical Frontier Corporation’s pharmaceutical division director and managing executive officer. “We are excited to join forces with Sorrento to bring SCILEX’s pipeline to the market in the near term.”
About Sorrento Therapeutics, Inc.
Sorrento is an antibody-centric, clinical stage biopharmaceutical company developing new treatments for pain management, cancer, inflammation and autoimmune diseases. Sorrento’s lead product candidates are late-stage biosimilar and biobetter antibodies, as well as clinical CAR-T therapies targeting solid tumors.
About Scilex Pharmaceuticals Inc.
Scilex Pharmaceuticals Inc., located in Malvern, PA, develops and brings branded pharmaceutical products to market using technologies that are designed to maximize quality of life for all. SCILEX is working to deliver the next generation of products that are responsible by design. SCILEX’s lead product candidate under development, ZTlido™ (lidocaine patch 1.8%), is a branded lidocaine patch formulation for the potential treatment of relieving the pain of postherpetic neuralgia, also referred to as after-shingles pain. For more information, visit www.scilexpharma.com. ZTlido™ is a trademark owned by Scilex Pharmaceuticals Inc. A proprietary name review by the FDA is planned.
About Scintilla Pharmaceuticals, Inc.
Scintilla Pharmaceuticals, Inc. is a subsidiary of Sorrento Therapeutics. Scintilla’s lead program is RTX for the treatment of opiate refractory cancer pain. The RTX program has been tested successfully in a Phase 1 – 2 clinical trial, and is scheduled to commence Phase 2 clinical trials in early 2017.
About Semnur Pharmaceuticals, Inc.
Semnur Pharmaceuticals, Inc. is a pharmaceutical company developing an injectable product for the treatment of lower back pain.
About ITOCHU and ICF
The history of ITOCHU Corporation dates back to 1858 when ITOCHU’s founder Chubei Itoh commenced linen trading operations. Since then, ITOCHU has evolved and grown over 150 years. With approximately 120 bases in 63 countries, ITOCHU, one of the leading sogo shosha, is engaging in domestic trading, import/export, and overseas trading of various products such as textile, machinery, metals, minerals, energy, chemicals, food, information and communications technology, realty, general products, insurance, logistics services, construction, and finance, as well as business investment in Japan and overseas. ICF is the core operation company with a mission, as a member of ITOCHU group, to contribute to improvement of the human health and life through its global business dealings in the field of pharmaceuticals, life-science products, performance products, specialty chemicals, and functional polymers.
Forward-Looking Statements
This press release and any statements made for and during any presentation or meeting contain forward-looking statements related to Sorrento Therapeutics, Inc. and its subsidiaries under the safe harbor provisions of Section 21E of the Private Securities Litigation Reform Act of 1995 and are subject to risks and uncertainties that could cause actual results to differ materially from those projected. Forward-looking statements include statements regarding the timing and potential benefits of the SCILEX transaction; the pending acquisition of Semnur by Scintilla; the expected timing for closing the acquisition of Semnur by Scintilla; the timing and outcomes of clinical trials and FDA actions and approvals for the RTX program and ZTlido™; statements regarding the timing for re-submitting an NDA for the ZTlido™ product candidate, as well as the potential timing for approval of the NDA; expectations regarding Scintilla’s and SCILEX’s technologies; expectations for Sorrento’s and its subsidiaries’ technologies and collaborations; and Scintilla’s and SCILEX’s prospects. Risks and uncertainties that could cause our actual results to differ materially and adversely from those expressed in our forward-looking statements, include, but are not limited to: risks related to Sorrento’s and its subsidiaries’ technologies and prospects; risks related to ZTlido™; risks related to the completion of the proposed acquisition of Semnur by Scintilla; risks related to seeking regulatory approvals and conducting clinical trials; and other risks that are described in Sorrento’s most recent periodic reports filed with the Securities and Exchange Commission, including Sorrento’s Annual Report on Form 10-K for the year ended December 31, 2015, as amended. Investors are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date of this release and we undertake no obligation to update any forward-looking statement in this press release except as required by law.
Sorrento® and the Sorrento logo are registered trademarks of Sorrento Therapeutics, Inc.
All other trademarks and trade names are the property of their respective owners.
NEW YORK, Nov. 08, 2016 — Progenics Pharmaceuticals, Inc. (Nasdaq:PGNX), an oncology company developing innovative medicines and other products for targeting and treating cancer, today announced that Mark Baker, Chief Executive Officer, will present at two upcoming investor conferences:
- Presentation at the Stifel 2016 Healthcare Conference on Tuesday, November 15, 2016 at 3:45 p.m. Eastern Time. The conference is being held at the Lotte New York Palace Hotel in New York City.
- Presentation at the Jefferies London Healthcare Conference on Thursday, November 17, 2016 at 9:20 a.m. Greenwich Mean Time. The conference is being held at the Waldorf Hilton in London, UK.
A live webcast of both the Stifel and Jefferies presentations will be available in the Media Center of the Progenics website, www.progenics.com. To ensure a timely connection, users should register at least 15 minutes prior to the scheduled start. An archive of the events will be available for 90 days.
About Progenics
Progenics Pharmaceuticals, Inc. is developing innovative medicines and other products for targeting and treating cancer, with a pipeline that includes several product candidates in later-stage clinical development. These products in development include therapeutic agents designed to precisely target cancer (AZEDRA® and 1095), and PSMA-targeted imaging agents for prostate cancer (1404 and PyLTM) intended to enable clinicians and patients to accurately visualize and manage their disease. In addition, in late 2015 Progenics acquired EXINI Diagnostics AB, a leader in the development of advanced artificial intelligence-based imaging analysis tools and solutions for medical decision support. The acquisition of EXINI complements Progenics’ strategy to support its imaging and therapeutic agents with sophisticated analytical tools and other technologies to help physicians and patients visualize, understand, target and treat cancer. Progenics’ first commercial product, RELISTOR® (methylnaltrexone bromide) for opioid-induced constipation, is partnered with and marketed by Valeant Pharmaceuticals International, Inc.
This press release may contain projections and other “forward-looking statements” regarding future events. Statements contained in this communication that refer to Progenics’ estimated or anticipated future results or other non-historical facts are forward-looking statements that reflect Progenics’ current perspective of existing trends and information as of the date of this communication. Forward looking statements generally will be accompanied by words such as “anticipate,” “believe,” “plan,” “could,” “should,” “estimate,” “expect,” “forecast,” “outlook,” “guidance,” “intend,” “may,” “might,” “will,” “possible,” “potential,” “predict,” “project,” or other similar words, phrases or expressions. Such statements are predictions only, and are subject to risks and uncertainties that could cause actual events or results to differ materially. These risks and uncertainties include, among others, the cost, timing and unpredictability of results of clinical trials and other development activities and collaborations, such as our collaboration with Valeant on the RELISTOR oral formulation and the Phase 3 clinical program for 1404; our ability to successfully integrate EXINI Diagnostics AB and to develop and commercialize its products; the unpredictability of the duration and results of regulatory review of New Drug Applications and Investigational NDAs; market acceptance for approved products; the effectiveness of the efforts of our partners to market and sell products on which we collaborate and the royalty revenue generated thereby; generic and other competition; the possible impairment of, inability to obtain and costs of obtaining intellectual property rights; possible product safety or efficacy concerns, general business, financial and accounting matters, litigation and other risks. More information concerning Progenics and such risks and uncertainties is available on its website, and in its press releases and reports it files with the U.S. Securities and Exchange Commission. Progenics is providing the information in this press release as of its date and, except as expressly required by law, Progenics disclaims any intent or obligation to update or revise any forward-looking statements, whether as a result of new information, future events or circumstances or otherwise.
Additional information concerning Progenics and its business may be available in press releases or other public announcements and public filings made after this release. For more information, please visit www.progenics.com. Please follow us on LinkedIn®. Information on or accessed through our website or social media sites is not included in the company’s SEC filings.
(PGNX-F)

Contact:
Melissa Downs
Investor Relations
(646) 975-2533
mdowns@progenics.com
HOUSTON, Nov. 08, 2016 — SAExploration Holdings, Inc. (NASDAQ:SAEX), or SAE, today announced a new project award for seismic data acquisition services valued at approximately $35 million.
The award is for a 3D deep water ocean-bottom marine project in West Africa. SAE expects to initiate this project in late 2016 and complete it in the first quarter of 2017. This project will be performed using an advanced remotely-operated-vehicle deployment method in conjunction with ocean-bottom nodal seismic recording technology equipped to successfully operate in water depths ranging from zero to 3,000 meters deep.
SAE will utilize its currently available equipment and other external resources to execute the project with no new capital expenditures required.
About SAExploration Holdings, Inc.
SAE is an internationally-focused oilfield services company offering a full range of vertically-integrated seismic data acquisition and logistical support services in remote and complex environments throughout Alaska, Canada, South America and Southeast Asia. In addition to the acquisition of 2D, 3D, time-lapse 4D and multi-component seismic data on land, in transition zones and offshore in depths reaching 3,000 meters, SAE offers a full suite of logistical support and in-field data processing services, such as program design, planning and permitting, camp services and infrastructure, surveying, drilling, environmental assessment and reclamation and community relations. SAE operates crews around the world, performing major projects for its blue-chip customer base, which includes major integrated oil companies, national oil companies and large independent oil and gas exploration companies. Operations are supported through a multi-national presence in Houston, Alaska, Canada, Peru, Colombia, Bolivia, Brazil, New Zealand and Malaysia. For more information, please visit SAE’s website at www.saexploration.com.
The information in SAE’s website is not, and shall not be deemed to be, a part of this notice or incorporated in filings SAE makes with the Securities and Exchange Commission.
Forward Looking Statements
This press release contains certain “forward-looking statements” within the meaning of the U.S. federal securities laws with respect to SAE. These statements can be identified by the use of words or phrases such as “expects,” “estimates,” “projects,” “budgets,” “forecasts,” “anticipates,” “intends,” “plans,” “may,” “will,” “could,” “should,” “believes,” “predicts,” “potential,” “continue,” and similar expressions. These forward-looking statements include statements regarding SAE’s financial condition, results of operations and business and SAE’s expectations or beliefs concerning future periods and possible future events. These statements are subject to significant known and unknown risks and uncertainties that could cause actual results to differ materially from those stated in, and implied by, this press release. Risks and uncertainties that could cause actual results to vary materially from SAE’s expectations are described under “Risk Factors” and “Cautionary Note Regarding Forward-Looking Statements” in SAE’s Form 10-Q filed on November 4, 2016, for the period ended September 30, 2016. Except as required by applicable law, SAE is not under any obligation to, and expressly disclaims any obligation to, update or alter its forward looking statements, whether as a result of new information, future events, changes in assumptions or otherwise.

Contact
SAExploration Holdings, Inc.
Ryan Abney
Vice President, Capital Markets & Investor Relations
(281) 258-4409
rabney@saexploration.com
Earthstone Energy, Inc. Establishes Significant Operated Footprint in the Midland Basin
THE WOODLANDS, TX AND MIDLAND, TX / November 8, 2016 / Earthstone Energy, Inc. (NYSE MKT: ESTE) (“Earthstone”) and Bold Energy III LLC (“Bold”), a portfolio company of EnCap Investments L.P. (“EnCap”), today announced that they have entered into a definitive contribution agreement (the “Agreement”) under which Earthstone will acquire all of the outstanding membership interests of Bold, inclusive of producing assets and undeveloped acreage, in an “Up-C” transaction (the “Transaction”).
Upon completion of the Transaction, current Earthstone stockholders will own approximately 39% of the combined company, and Bold members will own the remaining 61% on a fully diluted basis. See “Transaction Details” and “Approvals” below.
The Transaction represents a transformational shift for Earthstone to a high-growth, Midland Basin-focused operating company. The existing Earthstone management team, including President and CEO, Frank A. Lodzinski, will lead the combined company. The combined company will maintain its headquarters in The Woodlands, Texas, and maintain an office in Midland, Texas, to provide for a seamless integration and development of Bold’s considerable, operated Midland Basin acreage position.
Highlights of Bold’s asset base and operations include:
- Approximately 20,900 net surface acres (62,500 net effective acres) in the core of the Midland Basin
- Approximately 16,000 net acres in Reagan County; 3,260 net acres in Upton County; 1,310 net acres in Midland County; and the remainder in Glasscock, Howard, and Martin Counties
- 99% operated, 85% average working interest on net operated acreage
- Approximately 500 gross highly prospective, largely de-risked operated horizontal drilling locations across multiple benches
- Vast majority in the Wolfcamp formation with remainder in the Lower Spraberry
- Further upside from future de-risking of additional Wolfcamp and Spraberry benches, increased drilling density, and potential acreage trades to create additional drilling locations
- EURs, normalized to 7,500 foot laterals, ranging from 700 MBoe to 1,000 MBoe (56% to 71% oil), with further upside from ongoing improvements in completion techniques
- Current net production of approximately 2,320 Boepd (63% oil) predominantly from 18 gross / 12.6 net horizontal operated Wolfcamp wells
- Expected 2016 exit rate of 2,640 Boepd (61% oil)
- Operating a one-rig drilling program, with two wells flowing back, one well being completed and six wells waiting on completion; one-rig program can satisfy all material leasehold obligations
Please see the Transaction presentation on Earthstone’s website, www.earthstoneenergy.com, for more details on Bold’s assets.
Highlights of the combined company include:
- Strong combined management and technical teams
- Mr. Lodzinski and his senior management team at Earthstone have a demonstrated track record of creating significant value for stockholders. Earthstone and prior entities have executed growth strategies, inclusive of substantial drilling programs, driven by technical talent and prudent capital structures
- Bold’s management and technical team have extensive experience in the Permian Basin and built a high-quality asset base through its business development, land, and operational efforts
- The combined company will have critical mass, compelling wellhead returns, and a seasoned management team that can raise capital to develop existing assets and pursue additional, accretive growth projects
- Clean balance sheet and significant liquidity position: As of September 30, 2016, the combined company had approximately $24.0 million of cash on-hand and $17.0 million of bank debt drawn against a combined $102.0 million reserve-based loan facility
- Current production of approximately 7,400 Boepd (63% oil), consisting of 46% from the Midland Basin, 38% from the Eagle Ford, and 16% from the Bakken and other areas
- Approximately 26,800 net surface acres (80,150 net effective acres) in the Midland Basin and 18,600 net surface acres in the Eagle Ford
- Includes Earthstone’s strong non-operated position in the core of the Midland Basin (Lynden Acquisition, closed May 2016) with 5,883 net acres (40% average working interest) in Howard, Glasscock, Martin, and Midland Counties with a prominent Permian Basin operator
- Approximately 715 gross drilling locations in the Midland Basin
- Operated (Bold Transaction): 500 gross locations (85% average working interest)
- Non-Operated (primarily Lynden Acquisition): 215 gross (35% average working interest)
- Additional locations expected from future de-risking of Wolfcamp and Spraberry benches, increased drilling density, and potential acreage trades to create more drilling locations
Frank A. Lodzinski, President and CEO of Earthstone, commented, “The Transaction is truly a transformative business combination that will allow Earthstone’s stockholders to enjoy the benefits of a much larger company that is still driven by a management team that has repeatedly proven itself in the public marketplace. Having successfully executed three meaningful transactions since December 2014, Earthstone continues to rapidly increase its production, reserves, and drilling inventory. The combination currently adds over 500 gross operated high potential proved and probable locations to our drilling inventory. We expect the number of locations to increase with further de-risking of Spraberry and Wolfcamp intervals. Additionally, we are excited about the upside in reserves and returns being realized from on-going improvements in completion techniques. We will immediately begin to integrate the operations and activities of the companies while we continue our pursuit of additional opportunities. We intend to continue our growth in the Permian basin via direct leasing, development, and M&A activities.”
Mr. Lodzinski further stated “We expect to issue 2017 company-wide guidance and a capital expenditure budget in early 2017 that will include significant capital devoted to the Midland Basin. Bold is currently running a one-rig program, and the combined company may add a second rig in the Midland Basin after the closing of this transaction, which is expected in the first quarter of 2017. With this combination, our strategic focus is clearly directed toward further building our operated asset base in the Permian Basin. Our Eagle Ford and Bakken assets provide a strong source of cash flow to support a significant combined borrowing base and to fund our acquisition and development activities. As we proceed to closing, we will further refine our capital allocation initiatives and advise the market appropriately”.
Joseph L. Castillo, President of Bold, commented, “Since April 2013, despite the significant downturn in commodity prices affecting the industry, we have established a production base and a significant acreage position in the core of the Midland Basin. We look forward to combining with Earthstone to continue the development of our acreage in Midland, Upton, and Reagan counties. Reagan County, in particular, has tremendous potential as we continue to drive down well costs and improve upon horizontal completion practices. We look forward to integrating our team into the combined company to advance our collective interests and portfolio of projects. I firmly believe this transaction will provide significant growth potential and is a path towards enhancing shareholder value.”
Transaction Details
The Transaction has been organized in a manner commonly known as an “Up-C” structure. Under this structure and the Agreement, Earthstone will recapitalize its common stock into two classes – Class A and Class B, and all its existing outstanding common stock will be converted into Class A common stock. Bold will purchase approximately 36.1 million shares of Earthstone’s Class B common stock for nominal consideration, with the Class B common stock having no economic rights in Earthstone other than voting rights on a pari passu basis with the Class A common stock. In addition, Earthstone has formed Earthstone Energy Holdings, LLC, a Delaware limited liability company (“EEH”). At closing, EEH will issue approximately 22.3 million of its membership units to Earthstone and one of Earthstone’s wholly-owned subsidiaries, in the aggregate, and 36.1 million membership units to Bold in exchange for each of the parties transferring all their assets to EEH. Each membership unit in EEH held by Bold, together with one share of Bold’s Class B common stock, will be convertible into Class A common stock on a one-for-one basis. Therefore, upon the closing of the transaction, stockholders of Earthstone and unitholders of Bold are expected to own approximately 39% and 61%, respectively, of the combined company’s then outstanding Class A and Class B common stock on a fully diluted basis. After closing, Earthstone will conduct its activities through EEH and be its sole managing member. The transaction is expected to close in the first quarter of 2017.
Approvals
A special committee of the board of directors of Earthstone has independently approved and recommended the Transaction to the full board of directors of Earthstone, which has unanimously approved the Agreement. The Transaction is further subject to the majority approval of Earthstone stockholders, including a majority of disinterested stockholders, as well as other customary approvals.
Complete details of the terms of the Transaction are set out in the Agreement, which will be filed by Earthstone and will be available for viewing under its profile at www.sec.gov.
Conference Call
In connection with Earthstone’s third quarter 2016 conference call scheduled for Wednesday, November 9, 2016 at 10:00 a.m. Eastern (9:00 a.m. Central), members of the Earthstone and Bold management teams will discuss the proposed Transaction. Investors may participate in the conference call via telephone by dialing 877-407-8035 for domestic callers or 201-689-8035 for international callers, and, in both cases, asking for the Earthstone conference. A replay of the call will be available on Earthstone’s website and by telephone until 11:59 p.m. Eastern (10:59 p.m. Central), Wednesday, November 23, 2016. The number for the replay is 877-481-4010 for domestic calls or 919-882-2331 for international calls, using Replay ID: 10135.
A profile of the proposed Transaction has been posted to Earthstone’s website at www.earthstoneenergy.com.
Advisors
Stephens Inc. acted as independent financial advisor and provided a fairness opinion to the special committee of the board of directors of Earthstone. Tudor, Pickering, Holt & Co. acted as financial advisor to Bold. Legal advisors included Richards, Layton & Finger for the special committee of the board of directors of Earthstone, Jones & Keller, P.C. for Earthstone, and Latham & Watkins LLP for Bold.
About Earthstone
Earthstone Energy, Inc. is a growth-oriented independent oil and gas exploration and production company engaged in developing and acquiring oil and gas reserves through an active and diversified program that includes acquiring, drilling and developing undeveloped leases, asset and corporate acquisitions and exploration activities, with its primary assets located in the Eagle Ford trend of south Texas, the Midland Basin of west Texas, and the Williston Basin of North Dakota. Earthstone is traded on NYSE MKT under the symbol “ESTE.”
Information on Earthstone can be found at www.earthstoneenergy.com. Earthstone’s corporate headquarters is located in The Woodlands, Texas.
Forward-Looking Statements
This release contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended (the “Securities Act”), and Section 21E of the Securities Exchange Act of 1934, as amended (the “Exchange Act”). Statements that are not strictly historical statements constitute forward-looking statements and may often, but not always, be identified by the use of such words such as “expects,” “believes,” “intends,” “anticipates,” “plans,” “estimates,” “potential,” “possible,” or “probable” or statements that certain actions, events or results “may,” “will,” “should,” or “could” be taken, occur or be achieved. The forward-looking statements include statements about the expected benefits of the proposed Transaction to Earthstone and its stockholders, the anticipated completion of the proposed Transaction or the timing thereof, the expected future reserves, production, financial position, business strategy, revenues, earnings, costs, capital expenditures and debt levels of the combined company, and plans and objectives of management for future operations. Forward-looking statements are based on current expectations and assumptions and analyses made by Earthstone and its management in light of experience and perception of historical trends, current conditions and expected future developments, as well as other factors appropriate under the circumstances. However, whether actual results and developments will conform to expectations is subject to a number of material risks and uncertainties, including but not limited to: the ability to obtain stockholder and regulatory approvals of the proposed Transaction; the ability to complete the proposed Transaction on anticipated terms and timetable; Earthstone’s ability to integrate its combined operations successfully after the Transaction and achieve anticipated benefits from it; the possibility that various closing conditions for the Transaction may not be satisfied or waived; risks relating to any unforeseen liabilities of Earthstone or Bold; declines in oil, natural gas liquids or natural gas prices; the level of success in exploration, development and production activities; adverse weather conditions that may negatively impact development or production activities; the timing of exploration and development expenditures; inaccuracies of reserve estimates or assumptions underlying them; revisions to reserve estimates as a result of changes in commodity prices; impacts to financial statements as a result of impairment write-downs; risks related to level of indebtedness and periodic redeterminations of the borrowing base under Earthstone’s credit agreement; Earthstone’s ability to generate sufficient cash flows from operations to meet the internally funded portion of its capital expenditures budget; Earthstone’s ability to obtain external capital to finance exploration and development operations and acquisitions; the ability to successfully complete any potential asset dispositions and the risks related thereto; the impacts of hedging on results of operations; uninsured or underinsured losses resulting from oil and natural gas operations; Earthstone’s ability to replace oil and natural gas reserves; and any loss of senior management or technical personnel. Earthstone’s annual report on Form 10-K for the year ended December 31, 2015, quarterly reports on Form 10-Q, recent current reports on Form 8-K, and other Securities and Exchange Commission (“SEC”) filings discuss some of the important risk factors identified that may affect Earthstone’s business, results of operations, and financial condition. Earthstone and Bold undertake no obligation to revise or update publicly any forward-looking statements except as required by law.
Additional Information About the Proposed Transaction
This release does not constitute an offer to sell or the solicitation of an offer to buy any securities or a solicitation of a vote or proxy.
In connection with the proposed Transaction, Earthstone will file with the SEC and mail to its security holders a proxy statement and other relevant documents. WE URGE INVESTORS AND SECURITY HOLDERS TO READ THE PROXY STATEMENT AND ANY OTHER RELEVANT DOCUMENTS WHEN THEY BECOME AVAILABLE, BECAUSE THEY WILL CONTAIN IMPORTANT INFORMATION about Earthstone and the proposed transaction. Investors and security holders will be able to obtain these materials (when they are available) and other documents filed with the SEC free of charge at the SEC’s website, www.sec.gov. In addition, a copy of the proxy statement (when it becomes available) may be obtained free of charge from Earthstone’s website at www.earthstoneenergy.com. Investors and security holders may also read and copy any reports, statements and other information filed by Earthstone, with the SEC, at the SEC public reference room at 100 F Street, N.E., Washington, D.C. 20549. Please call the SEC at 1-800-SEC-0330 or visit the SEC’s website for further information on its public reference room. In addition, the documents filed with the SEC by Earthstone can be obtained free of charge from Earthstone’s website at www.earthstoneenergy.com or by contacting Earthstone by mail at 1400 Woodloch Forest Drive, Suite 300, The Woodlands, TX, 77380, or by telephone at 281-298-4246.
Participants in the Solicitation
Earthstone and its directors, executive officers and certain other members of management and employees may be deemed to be participants in the solicitation of proxies in respect of the proposed Transaction. Information regarding Earthstone’s directors and executive officers is available in its proxy statement filed with the SEC by Earthstone on October 4, 2016 in connection with its 2016 annual meeting of stockholders. Other information regarding the participants in the proxy solicitation and a description of their direct and indirect interests, by security holdings or otherwise, will be contained in the proxy statement and other relevant materials to be filed with the SEC when they become available.
This release shall not constitute an offer to sell or the solicitation of any offer to buy any securities, nor shall there be any sale of securities in any jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such jurisdiction.
Contact
Neil K. Cohen
Vice President, Finance and Treasurer
Earthstone Energy, Inc.
1400 Woodloch Forest Drive, Suite 300
The Woodlands, TX 77380
281-298-4246
Unified Payments’ gift card software application is now available on Poynt’s smart payment terminal
MIAMI, FL–(Nov 8, 2016) – Net Element, Inc. (NASDAQ: NETE) (“Net Element” or the “Company”), a provider of global mobile payment technology solutions and value-added transactional services, announces the launch of its proprietary gift card application for smart payment terminals. Now available for retailers and merchants nationwide, the Unified Payments gift card application made its initial debut on Poynt’s (http://www.poynt.com) smart payment terminal at the Money 2020 event in Las Vegas.
Net Element’s omni-channel gift and loyalty platform enables small-to-medium size businesses to centralize their customer data spanning in-store, online, and via social and mobile channels. Building on this platform, the newly launched Unified Payments gift card application is now fully integrated with Poynt’s “terminal” and “register” applications and works seamlessly with any other payment acceptance application utilizing Poynt’s payment framework.
The Unified Payments application interface is intuitive and does not require any training for its many capabilities and features. Cashiers can issue new cards, add value, transfer value between cards, accept payment utilizing physical or virtual cards, void payment, check the card balance, and replace the card if needed. For full oversight, management has direct access to all gift card transactions via Poynt’s smart payment terminal large screen display as well as online on Net Element’s SalesCentral reporting system.
For merchants, the Unified Payments gift card program for smart payment terminals offers flexible methods to increase their cash flow. Merchants can seamlessly integrate multiple program types into a single gift card. Existing merchants can convert their gift card database into Unified Payments gift card platform at an affordable cost per customer.
Key Benefits of the Gift Card Program:
- Promotes sales and new products/services
- Creates individualized gifts for every occasion
- Boosts brand awareness and impulse purchasing
- Eliminates fraud and risk of double usage
- Provides complete transaction tracking
“We are pleased to introduce this new software application for smart payment terminals just in time for the 2016 holiday season,” comments Oleg Firer, CEO of Net Element. “In less than a month, and in close cooperation with our partners, our software engineers were able to successfully design, program and test the application on Poynt’s smart payment terminal. We are excited to offer this broad functionality gift card application on Poynt’s smart payment terminal. Our Unified Payment gift card application is available to all sales partners and merchants nationwide.”
About Net Element
Net Element, Inc. (NASDAQ: NETE) operates a payments-as-a-service transactional and value-added services platform for small to medium enterprise (“SME”) in the US and selected emerging markets. In the US, we are growing transactional revenue with innovative services including our cloud based, restaurant point-of-sale solution Aptito. Internationally, Net Element’s strategy is to leverage its omni-channel platform to deliver flexible offerings to emerging markets with diverse banking, regulatory and demographic conditions such as UAE, Kazakhstan, Kyrgyzstan and Azerbaijan where initiatives have been recently launched. Further information is available at www.netelement.com.
Forward-Looking Statements
This press release contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. Any statements contained in this press release that are not statements of historical fact may be deemed forward-looking statements. Words such as “continue,” “will,” “may,” “could,” “should,” “expect,” “expected,” “plans,” “intend,” “anticipate,” “believe,” “estimate,” “predict,” “potential,” and similar expressions are intended to identify such forward-looking statements. These forward-looking statements include, without limitation, whether the gift card application for smart payment terminals will be widely adopted or result in additional business for the Company, whether Net Element can secure any additional financing and if such additional financing will be adequate to meet the Company’s objectives. All forward-looking statements involve significant risks and uncertainties that could cause actual results to differ materially from those expressed or implied in the forward-looking statements, many of which are generally outside the control of Net Element and are difficult to predict. Examples of such risks and uncertainties include, but are not limited to: (i) Net Element’s ability (or inability) to obtain additional financing in sufficient amounts or on acceptable terms when needed; (ii) Net Element’s ability to maintain existing, and secure additional, contracts with users of its payment processing services; (iii) Net Element’s ability to successfully expand in existing markets and enter new markets; (iv) Net Element’s ability to successfully manage and integrate any acquisitions of businesses, solutions or technologies; (v) unanticipated operating costs, transaction costs and actual or contingent liabilities; (vi) the ability to attract and retain qualified employees and key personnel; (vii) adverse effects of increased competition on Net Element’s business; (viii) changes in government licensing and regulation that may adversely affect Net Element’s business; (ix) the risk that changes in consumer behavior could adversely affect Net Element’s business; (x) Net Element’s ability to protect its intellectual property; (xi) local, industry and general business and economic conditions; (xii) adverse effects of potentially deteriorating U.S.-Russia relations, including, without limitation, over a conflict related to Ukraine, including a risk of further U.S. government sanctions or other legal restrictions on U.S. businesses doing business in Russia. Additional factors that could cause actual results to differ materially from those expressed or implied in the forward-looking statements can be found in the most recent annual report on Form 10-K and the subsequently filed quarterly reports on Form 10-Q and current reports on Form 8-K filed by Net Element with the Securities and Exchange Commission. Net Element anticipates that subsequent events and developments may cause its plans, intentions and expectations to change. Net Element assumes no obligation, and it specifically disclaims any intention or obligation, to update any forward-looking statements, whether as a result of new information, future events or otherwise, except as expressly required by law.
Regains Compliance with NASDAQ Listing Rule 5605(c)(2)(A)
MORRISTOWN, N.J., Nov. 07, 2016 — Pernix Therapeutics Holdings, Inc. (NASDAQ:PTX), a specialty pharmaceutical company with a focus on Pain and CNS conditions, today announced the appointment of Graham G. Miao, Ph.D. and Dennis H. Langer, M.D., J.D. to its Board of Directors, effective immediately. The Board also determined that Dr. Langer is an independent director and appointed him as chairperson of the Compensation Committee and as a member of the Audit and Nominating Committees. Accordingly, Pernix regained compliance with NASDAQ Listing Rule 5605(c)(2)(A), which requires Pernix to have at least three independent directors on its Audit Committee for continued listing on The NASDAQ Global Market.
“I’m pleased to welcome Dr. Miao and Dr. Langer to the Board,” said John Sedor, Chairman and Chief Executive Officer. “Dr. Miao and Dr. Langer are industry leaders. Their breadth of knowledge and experience will provide invaluable insight to Pernix as we move forward with the vision that I outlined when I first took over as Chief Executive Officer – to grow our current brands, pursue other growth opportunities and, ultimately, maximize shareholder value.”
Dr. Miao has served as Pernix’s President and Chief Financial Officer since July 2016. He was Senior Advisor to the Pernix interim CEO and Board of Directors from May 2016 to July 2016. Prior to joining Pernix, Dr. Miao served as Executive Vice President, Chief Financial Officer of PDI, Inc., a NASDAQ listed healthcare commercialization and molecular diagnostic company, from October 2014 until March 2016. In this role, he helped achieve double-digit revenue growth and lead the successful sale of PDI’s contract sales business to Publicis Healthcare. From September 2011 to September 2014, Dr. Miao served as Executive Vice President and Chief Financial Officer and held the additional role as Co-President and Co-Chief Executive Officer from September 2013 to September 2014 of Delcath Systems, Inc., a NASDAQ traded specialty pharmaceutical and medical device company focused on cancer treatment. From September 2009 until September 2011, Dr. Miao served as Chief of Staff for the Global CFO Organization at Dun & Bradstreet Corporation. Previously, Dr. Miao held senior management roles including EVP and CFO at Pagoda Pharmaceuticals and Vice President of Strategic Planning & Financial Analysis at Symrise Inc. He also worked at Schering-Plough Corporation, serving as division CFO for the company’s $3 billion primary care pharmaceuticals franchise. Dr. Miao held management roles at Pharmacia Corporation, including division CFO for the company’s $1.3 billion Global Oncology franchise where he led finance teams across marketing, sales, medical affairs, business development, and mergers & acquisitions. Earlier in his career, Dr. Miao worked as a biotechnology equity analyst at J.P. Morgan and a research scientist at Roche. Dr. Miao earned an M.B.A. in Finance and a Ph.D., M.Phil., M.A. in Biological Sciences from Columbia University, an M.S. in Molecular Biology from Arizona State University, and a B.S. in Biology from Fudan University.
Dr. Langer has served as director of several biotechnology, specialty pharmaceutical, and diagnostic companies, and has been CEO and/or co-founder of several health care companies. From January 2013 to July 2014 he served as Chairman and Chief Executive Officer of AdvanDx, Inc., a healthcare solutions company. From 2005 to 2010, Dr. Langer served as a Managing Partner of Phoenix IP Ventures, a private equity/venture capital firm specializing in life sciences. Previously, he was President, North America, of Dr. Reddy’s Laboratories, Limited, a multinational pharmaceutical company. From September 1994 until January 2004, Dr. Langer held several high-level positions at GlaxoSmithKline plc, and its predecessor, SmithKline Beecham, including most recently as a Senior Vice President of Research and Development. Prior to SmithKline Beecham, Dr. Langer was President and CEO of Neose Technologies, Inc. and before that held R&D and marketing positions at pharmaceutical companies Eli Lilly and Company, Abbott Laboratories and G. D. Searle & Company. At the beginning of his career, he was a Chief Resident at Yale University School of Medicine, and held clinical fellowships at Harvard Medical School and the National Institutes of Health. Dr. Langer currently serves as a Director of Myriad Genetics, Inc., Dicerna Pharmaceuticals, Inc., and several private companies. Dr. Langer served as a Director of several pharmaceutical and biotechnology companies, including Auxilium Pharmaceuticals, Inc., Ception Therapeutics, Inc. (acquired by Cephalon, Inc.), Cytogen Corporation, (acquired by EUSA Pharma, Inc.) Delcath Systems, Inc., Myrexis, Inc. Pharmacopeia, Inc. (acquired by Ligand Pharmaceuticals, Inc.), Sirna Therapeutics, Inc. (acquired by Merck & Co., Inc.), and Transkaryotic Therapies, Inc. (acquired by Shire plc). Dr. Langer is a Clinical Professor, Department of Psychiatry, Georgetown University School of Medicine. Dr. Langer received a J.D. from Harvard Law School, a M.D. from Georgetown University School of Medicine, and a B.A. in Biology from Columbia University.
About Pernix Therapeutics
Pernix Therapeutics is a specialty pharmaceutical business with a focus on acquiring, developing and commercializing prescription drugs primarily for the U.S. market. The Company targets underserved therapeutic areas such as CNS, including neurology and pain management, and has an interest in expanding into additional specialty segments. The Company promotes its branded products to physicians through its integrated Pernix sales force and markets its generic portfolio through its wholly owned subsidiaries, Macoven Pharmaceuticals, LLC and Cypress Pharmaceutical, Inc.
To learn more about Pernix Therapeutics, visit www.pernixtx.com.

CONTACT
Investor Relations
Matthew P. Duffy, 212-915-0685
LifeSci Advisors, LLC
matthew@lifesciadvisors.com
LEXINGTON, MA–(Nov 7, 2016) – Aldeyra Therapeutics, Inc. (NASDAQ: ALDX) (Aldeyra), a biotechnology company focused on the development of products to treat diseases related to aldehydes, today announced an upcoming poster presentation at the 2016 American College of Allergy, Asthma and Immunology Annual Scientific Meeting to be held November 10th -14th in San Francisco, CA. The presentation will summarize the results of a Phase 2 clinical trial of ADX-102 topical ophthalmic solution in a challenge model of allergic conjunctivitis in 100 subjects.
Details of the presentation are as follows:
- Title: A Randomized Double-Masked Phase 2 Clinical Trial of NS2 Ophthalmic Solution in Allergic Conjunctivitis
- Date: Saturday November 12that 1:00 p.m.
- Location: Moscone West Convention Center – Monitor No. 8
- Presented by: David Clark, M.D., M.R.C.P., A.F.P.M, Chief Medical Officer of Aldeyra Therapeutics
- Poster #: P316
The data represent the first demonstration of the clinical efficacy of aldehyde trapping in human disease, and support the continued development of ADX-102 in allergic conjunctivitis and other inflammatory diseases.
About Aldeyra Therapeutics
Aldeyra Therapeutics, Inc. is a biotechnology company devoted to improving lives by inventing, developing and commercializing products that treat diseases thought to be related to endogenous aldehydes, a naturally occurring class of pro-inflammatory and toxic molecules. Aldeyra’s lead product candidate, ADX-102, is an aldehyde trap in development for ocular inflammation, as well as for Sjögren-Larsson Syndrome and Succinic Semi-Aldehyde Dehydrogenase Deficiency, two inborn errors of aldehyde metabolism. Aldeyra’s product candidates have not been approved for sale in the U.S. or elsewhere.
About Allergic Conjunctivitis
Allergic conjunctivitis is a common allergic disease that is thought to be mediated in part by pro-inflammatory aldehydes, and is characterized by inflammation of the conjunctiva (a membrane covering part of the front of the eye), resulting in ocular itching, excessive tear production, lid swelling and redness.
Cautionary statement regarding forward-looking statements
Aldeyra cautions investors that any forward-looking statements or projections made by Aldeyra, including those made in this announcement, are subject to risks and uncertainties that may cause actual results to differ materially from those projected. Such factors include, but are not limited to, those described in the “Risk Factors” and “Management’s Discussion and Analysis of Financial Condition and Results of Operations” sections of Aldeyra’s Annual Report on Form 10-K for the year ended December 31, 2015 and Quarterly Report on Form 10-Q for the quarter ended June 30, 2016, which are on file with the Securities and Exchange Commission (SEC) and available on the SEC’s website at www.sec.gov. Additional factors may be set forth in Aldeyra’s Quarterly Report on Form 10-Q for the quarter ending September 30, 2016, to be filed with the SEC in the fourth quarter of 2016.
Corporate Contact:
Stephen Tulipano
Aldeyra Therapeutics, Inc.
Tel: +1 781-761-4904 Ext. 205
Email Contact
Investor Contact:
Chris Brinzey
Westwicke Partners
Tel: 339-970-2843
Email Contact
Media Contact:
Cammy Duong
MacDougall Biomedical Communications
781-591-3443
Email Contact
The partnership accelerates early-market adoption of Energous’ disruptive WattUp wireless charging technology with Dialog as the exclusive supplier
SAN JOSE, CA–(November 07, 2016) – Energous Corporation (NASDAQ: WATT), the developer of WattUp®, a revolutionary wire-free charging technology that provides over-the-air power at a distance, today announced a strategic partnership with Dialog Semiconductor plc (XETRA: DLG), a provider of highly-integrated power management, AC/DC power conversion, solid state lighting (SSL) and Bluetooth® low-energy (LE) technology. Dialog has agreed to make a strategic $10 million investment in Energous and become the exclusive component supplier of the WattUp technology, while Energous is able to leverage Dialog’s broad sales and distribution channels to accelerate market adoption.
Energous’ WattUp technology provides a unique and more extensive wireless-charging experience compared to traditional, coil-based technologies. By sending energy safely through the air using radio frequencies, WattUp is able to deliver intelligent, scalable power in a similar way to a Wi-Fi router. WattUp differs from inductive or resonant wireless charging systems in that it delivers power at a distance, to multiple devices, in any orientation, resulting in a wire-free experience that has the ability to transform the way consumers and industries charge and power electronic devices at home, in the office, in the car and beyond.
The strategic relationship will enhance the existing synergies between Energous’ uncoupled wireless charging technology and Dialog’s power saving technologies. Energous WattUp technology uses Dialog’s SmartBond® Bluetooth low energy solution as the out-of-band communications channel between the wireless transmitter and receiver. Dialog’s power management technology is then used to distribute power from the WattUp receiver integrated circuit (IC) to the rest of the device while Dialog’s AC/DC Rapid Charge™ power conversion technology efficiently delivers power to the wireless transmitter.
WattUp uses small form factor antennas that are formed using the existing device’s printed circuit board, removing the need for larger, more expensive coils. This enables broader adoption of wireless charging in a larger range of battery-powered devices, such as smartphones, tablets, Internet of Things (IoT) devices, small form factor wearables, gaming and Virtual Reality (VR)/Augmented Reality (AR) devices.
“Energous’ WattUp technology can be thought of as wireless charging 2.0, and could deliver a wireless charging experience that is much closer to what consumers imagine by charging devices close up and at a distance, while in use and without compromising product design or adding excessive cost,” said Mark Tyndall, Senior Vice President, Corporate Development and Strategy, Dialog Semiconductor. “This strategic partnership means that Dialog is able to more closely align our synergistic technologies, supply chain and global sales resources to accelerate the deployment of Energous’ WattUp wireless transmitter and receiver technology while expanding our innovative use cases and market share.”
“The partnership brings two very complementary companies closer together, creating numerous synergies and benefits,” said Stephen R. Rizzone, President and CEO, Energous. “Energous is pleased to be able to leverage Dialog’s decades of experience in power-saving technologies as well as its robust sales channel, long term strategic relationships and world-class fab and backend operations. Working together, we will be able to accelerate the adoption of the WattUp technology and reshape the way electronic devices are charged.”
“The partnership with a top-tier semiconductor company like Dialog also represents a strong validation for Energous as we prepare to launch WattUp-enabled consumer products with our licensees in early 2017,” added Rizzone.
The strategic partnership includes positive tactical and strategic implications that will aggressively speed up customer adoption of WattUp-enabled products and streamline chip production. Benefits of the agreement include joint marketing and sales operations, including access to Dialog’s channel partners and access to Dialog’s customer base to accelerate the adoption of WattUp in smartphone and emerging IoT applications.
Energous will be showcasing the WattUp technology at CES from January 5-8, 2017 in Dialog’s demo suite located in the Venetian Palazzo Hospitality Suites as well as Energous’ demo suite located in the Hard Rock Hotel Penthouse Suite.
For more information on Dialog Semiconductor’s power management technologies, visit www.dialog-semiconductor.com/power-management.
About Energous Corporation
Energous Corporation is the developer of WattUp® — an award-winning, wire-free charging technology that will transform the way consumers and industries charge and power electronic devices at home, in the office, in the car and beyond. WattUp is a revolutionary radio frequency (RF) based charging solution that delivers intelligent, scalable power via radio bands, similar to a Wi-Fi router. WattUp differs from current wireless charging systems in that it delivers contained power, at a distance, to multiple devices — thus resulting in a wire-free experience that saves users from having to remember to plug in their devices. For more information, please visit Energous.com, or follow Energous on Twitter and Facebook.
Safe Harbor Statement
This press release contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, that are intended to be covered by the “safe harbor” created by those sections. Forward-looking statements, which are based on certain assumptions and describe our future plans, strategies and expectations, can generally be identified by the use of forward-looking terms such as “believe,” “expect,” “may,” “will,” “should,” “could,” “seek,” “intend,” “plan,” “estimate,” “anticipate” or other comparable terms. All statements in this release that are not based on historical fact are “forward-looking statements.” Examples of forward-looking statements include, among others, statements we make regarding expectations for market developments, technological advances, anticipated results of our development efforts, and the timing for receipt of required regulatory approvals and product launches. While management has based any forward-looking statements included in this release on its current expectations, the information on which such expectations were based may change. Forward-looking statements involve inherent risks and uncertainties which could cause actual results to differ materially from those in the forward-looking statements. Important factors that could cause our actual results and financial condition to differ materially from those indicated in the forward-looking statements include, among others, the following: our ability to develop a commercially feasible technology; receipt of necessary regulatory approvals; our ability to find and maintain development partners and licensees, market acceptance of our technology, the amount and nature of competition in our industry; our ability to protect our intellectual property; and the other risks and uncertainties described in the Risk Factors and in Management’s Discussion and Analysis of Financial Condition and Results of Operations sections of our most recent annual report on Form 10-K and any subsequent quarterly reports on Form 10-Q. We urge you to consider those risks and uncertainties in evaluating our forward-looking statements. We caution readers not to place undue reliance upon any such forward-looking statements, which speak only as of the date made. Except as otherwise required by the federal securities laws, we disclaim any obligation or undertaking to publicly release any updates or revisions to any forward-looking statement contained herein (or elsewhere) to reflect any change in our expectations with regard thereto or any change in events, conditions or circumstances on which any such statement is based.
About Dialog Semiconductor
Dialog Semiconductor is a leading provider of integrated circuits (ICs) that power the Internet of Things. Dialog solutions are integral to some of today’s leading mobile devices and the enabling element for increasing performance and productivity on the go. From making smartphones more power efficient, enabling home appliances to be controlled from anywhere, to connecting the next generation of wearable devices, Dialog’s decades of experience and world-class innovation help manufacturers get to what’s next.
Dialog operates a fabless business model and is a socially responsible employer pursuing many programs to benefit the employees, community, other stakeholders and the environment we operate in. Dialog Semiconductor plc is headquartered in London with a global sales, R&D and marketing organization. In 2015, it had approximately $1.35 billion in revenue and was one of the fastest growing European public semiconductor companies. It currently has approximately 1,680 employees worldwide. The company is listed on the Frankfurt (FRANKFURT: DLG) stock exchange (Regulated Market, Prime Standard, ISIN GB0059822006) and is a member of the German TecDax index.
For more information, visit www.dialog-semiconductor.com.
Dialog, the Dialog logo, SmartBond and Rapid Charge are trademarks of Dialog Semiconductor plc or its subsidiaries. All other product or service names are the property of their respective owners. © Copyright 2016 Dialog Semiconductor All rights reserved.
Public Relations Contact:
Edelman
Alexandra Kenway
(650) 762-2985
PR@energous.com
Investor Relations Contact:
Pondel Wilkinson
Laurie Berman
(310) 279-5962
IR@energous.com
Cellvation to Advance Three Programs Licensed from UTHealth
Two Phase 2 Studies Supported by Approximately $10M in Secured Grant Funding
Frank Taffy to Serve as Interim Chief Executive Officer
NEW YORK, Nov. 07, 2016 — Fortress Biotech, Inc., (NASDAQ:FBIO) has formed a new subsidiary company, Cellvation, Inc., to develop novel therapies for the treatment of traumatic brain injury (“TBI”). Cellvation has entered into an agreement with The University of Texas Health Science Center at Houston (UTHealth) to secure exclusive worldwide rights to three programs for TBI, including two Phase 2 cell therapies.
For the pediatric population, a randomized, multi-center, double-blind, placebo-controlled, Phase 2 study of autologous bone marrow-derived stem cells for the treatment of severe TBI is ongoing and will enroll up to 50 patients (ClinicalTrials.gov Identifier: NCT01851083). For adults, a soon-to-be-commenced, randomized, double-blind, placebo-controlled, Phase 2 study of autologous bone marrow-derived stem cells for the treatment of severe TBI will enroll up to 55 patients (ClinicalTrials.gov Identifier: NCT02525432). The Phase 2 studies are supported by secured grants of approximately $10 million from the National Institutes of Health and the Department of Defense. Cellvation plans to strategically supplement this grant funding to open additional clinical sites and accelerate study outcomes.
According to the Centers for Disease Control and Prevention, TBI is a leading cause of death and disability in adults and children in the United States, contributing to almost one third of all injury-related mortalities. TBI results from a trauma or jolt to the head (or a penetrating head injury) that impacts normal brain function. TBIs range in severity from “mild” (a brief change in mental status or consciousness, often referred to as a concussion) to “severe” (an extended period of unconsciousness typically requiring hospitalization). Based on the National Hospital Discharge Survey, there were approximately 2.5 million TBIs in the United States in 2010, which resulted in more than 50,000 deaths and 280,000 hospitalizations. Injuries associated with TBI cost an estimated $76 billion annually in the United States.
Cellvation also licensed rights from UTHealth to a next-generation bioreactor that enhances the anti-inflammatory potency of bone marrow-derived cells without genetic manipulation. As Cellvation continues clinical development of its lead programs in the United States, it will explore early market entry in Japan under the recently revised Pharmaceutical Affairs Law, which provides for conditional approval of regenerative medicine products upon demonstration of safety and efficacy in early clinical studies.
The Cellvation programs were developed by Dr. Charles Cox, George & Cynthia Mitchell Distinguished Chair in Neurosciences; Director, Children’s Regenerative Medicine, McGovern Medical School at the UTHealth Department of Pediatric Surgery; and Co-Director of the Memorial Hermann Red Duke Trauma Institute. Dr. Cox will serve as a key scientific advisor to the Company. “Cellular therapies are a highly promising strategy to mitigate the neuroinflammatory response to TBI that amplifies the initial injury,” said Dr. Cox. “Targeting this ‘secondary brain injury’ is designed to preserve injured tissue and ultimately improve outcomes. We are excited to work with the Cellvation team to advance these important programs.”
Dr. Lindsay A. Rosenwald, Chairman and CEO of Fortress Biotech, stated, “We are pleased to enter into this collaboration with UTHealth and Dr. Charles Cox. TBI is associated with significant unmet medical need and a standard of care that hasn’t evolved much over the past two decades. Data generated by Dr. Cox and his team suggest a cell therapy could reduce further injury following a head trauma and improve long-term outcomes. We look forward to continuing development of these exciting therapies and delivering them to the bedside.”
Fortress also announced the appointment of Frank Taffy as interim Chief Executive Officer, President and member of Cellvation’s Board of Directors. Mr. Taffy identified the Cellvation programs and co-founded the company. He has more than 15 years of experience in life sciences corporate development and operations. Mr. Taffy currently serves as President, Chief Executive Officer and member of the Board of Directors for Helocyte, Inc., a company he also co-founded that is focused on the development of novel immunotherapies for cancer and infectious disease. He previously held the positons of Head (Senior Director) of Business Affairs at Forest Laboratories (now Allergan) and Director of Corporate Development at Life Technologies (now Thermo Fisher Scientific), where he also held Board positions on behalf of the company. Mr. Taffy began his career as Counsel for Intellectual Property at Procter & Gamble. He holds a J.D. from Syracuse University College of Law and a B.A. in biochemistry from the University of North Texas.
About Bone Marrow-Derived Stem Cells for the Treatment of Traumatic Brain Injury
Traumatic brain injury (“TBI”) remains one of the greatest unsolved problems in clinical trauma care today. Cell-based therapy is distinguished from small molecule strategies by the pleiotropic mechanisms of action that have been determined in preclinical data and an excellent safety profile in early clinical trials. Proof of concept data have been developed using bone marrow mononuclear cells in both stroke and TBI, and these data formed the foundation for translation into Phase 1 and 2 clinical trials at UTHealth. The mechanism of action appears to be related to down-regulation of neuroinflammatory response of the innate immune system. Cellvation further licensed rights from UTHealth to a novel bioreactor that amplifies anti-inflammatory gene programs in adherent bone marrow derived mesenchymal stromal cells without external gene transfection approaches. The utility of this approach has been confirmed using in vivo models of TBI. Development of this pipeline of cellular therapeutics represents an opportunity to fundamentally change the approach to TBI treatment.
About The University of Texas Health Science Center at Houston
Established in 1972 by The University of Texas System Board of Regents, The University of Texas Health Science Center at Houston (UTHealth) is Houston’s Health University and Texas’ resource for health care education, innovation, scientific discovery and excellence in patient care. The most comprehensive academic health center in The UT System and the U.S. Gulf Coast region, UTHealth is home to schools of biomedical informatics, biomedical sciences, dentistry, nursing and public health and the John P. and Kathrine G. McGovern Medical School. UTHealth includes The University of Texas Harris County Psychiatric Center and a growing network of clinics throughout the region. The university’s primary teaching hospitals include Memorial Hermann-Texas Medical Center, Children’s Memorial Hermann Hospital and Harris Health Lyndon B. Johnson Hospital. For more information, visit www.uth.edu.
UTHealth is a leader in cell therapeutics for neurological injury and has developed novel approaches to the treatment of traumatic brain injury. McGovern Medical School at UTHealth is a collaborator with Memorial Hermann-Texas Medical Center in the Memorial Hermann Red Duke Trauma Institute and Memorial Hermann Mischer Neuroscience Institute. Memorial Hermann-TMC is one of the busiest Level 1 American College of Surgeons-verified Adult and Pediatric Trauma Centers in the country.
About Fortress Biotech
Fortress Biotech, Inc. (“Fortress”) is a biopharmaceutical company dedicated to acquiring, developing and commercializing novel pharmaceutical and biotechnology products. Fortress develops and commercializes its products both within Fortress and through subsidiary companies, also known as Fortress Companies, and also develops other products relating to financial services through its affiliate, National Holdings Corporation (NASDAQ:NHLD). In addition to its internal development programs, Fortress leverages its biopharmaceutical business expertise and drug development capabilities and provides funding and management services to help the Fortress Companies achieve their goals. Fortress and the Fortress Companies may seek licensing, acquisitions, partnerships, joint ventures and/or public and private financings to accelerate and provide additional funding to support their research and development programs. For more information, visit www.fortressbiotech.com.
Forward-Looking Statements
This press release may contain “forward-looking statements” within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934. Such statements include, but are not limited to, any statements relating to our growth strategy and product development programs and any other statements that are not historical facts. Forward-looking statements are based on management’s current expectations and are subject to risks and uncertainties that could negatively affect our business, operating results, financial condition and stock price. Factors that could cause actual results to differ materially from those currently anticipated include: risks related to our growth strategy; risks relating to the results of research and development activities; our ability to obtain, perform under and maintain financing and strategic agreements and relationships; uncertainties relating to preclinical and clinical testing; our dependence on third party suppliers; our ability to attract, integrate, and retain key personnel; the early stage of products under development; our need for substantial additional funds; government regulation; patent and intellectual property matters; competition; as well as other risks described in our SEC filings. We expressly disclaim any obligation or undertaking to release publicly any updates or revisions to any forward looking statements contained herein to reflect any change in our expectations or any changes in events, conditions or circumstances on which any such statement is based, except as may be required by law.

Contacts:
Cellvation, Inc.
Frank Taffy, Co-Founder, Interim CEO, President, Board Member
(212) 554-4520
frank@helocyte.com
Fortress Biotech, Inc.
Lucy Lu, MD, Executive Vice President & Chief Financial Officer
(781) 652-4500
ir@fortressbiotech.com
Fortress Biotech Media Relations
Laura Bagby
6 Degrees
(312) 448-8098
lbagby@6degreespr.com
UTHealth Media Relations
Charles Cox, M.D.
Via Deborah Mann Lake
(713) 500-3030
Deborah.m.lake@uth.tmc.edu
– Second Positive Phase 3 Study Provides Further Evidence of SPINRAZA’s Efficacy and Favorable Safety Profile –
– Results Were Statistically Significant and Clinically Meaningful –
Biogen (NASDAQ:BIIB) and Ionis Pharmaceuticals (NASDAQ:IONS) announced that SPINRAZATM (nusinersen), an investigational treatment for spinal muscular atrophy (SMA), met the primary endpoint at the interim analysis of CHERISH, the Phase 3 study evaluating SPINRAZA in later-onset (consistent with Type 2) SMA. The analysis found that children receiving SPINRAZA experienced a highly statistically significant improvement in motor function compared to those who did not receive treatment. SPINRAZA demonstrated a favorable safety profile in the study.
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“These results, along with our successful trial in infantile-onset SMA, reinforce the potential of SPINRAZA to benefit a broad range of SMA patients,” said Michael Ehlers, M.D., Ph.D., executive vice president, head of Research and Development at Biogen. “We will make regulators around the globe aware of this data and will continue working closely with them to bring SPINRAZA to families affected by SMA as quickly as possible.”
Biogen is preparing for the potential launch of SPINRAZA in the U.S. possibly as early as the end of 2016 or the first quarter of 2017.
Results From the CHERISH Interim Analysis
CHERISH is a fifteen-month study investigating SPINRAZA in 126 non-ambulatory patients with later-onset SMA (consistent with Type 2), including patients with the onset of signs and symptoms at greater than 6 months and an age of 2 to 12 years at screening.
Results from the primary endpoint of the pre-specified interim analysis demonstrated a difference of 5.9 points (p= 0.0000002) at 15 months between the treatment (n=84) and sham-controlled (n=42) study arms, as measured by the Hammersmith Functional Motor Scale Expanded (HFMSE). From baseline to 15 months of treatment, patients who received SPINRAZA achieved a mean improvement of 4.0 points in the HFMSE, while patients who were not on treatment declined by a mean of 1.9 points. The HFMSE is a reliable and validated tool specifically designed to assess motor function in children with SMA, and a change of three points or greater in the HFMSE has previously been identified as clinically meaningful. Data from the other endpoints analyzed were consistently in favor of children who received treatment. SPINRAZA demonstrated a favorable safety profile. The majority of the adverse events were considered to be either related to SMA disease, common events in the general population, or events related to the lumbar puncture procedure. No patients discontinued the study.
With the positive interim analysis, the CHERISH study will be stopped and participants will be able to transition into the SHINE open-label extension study to receive SPINRAZA. Full study results will be presented at future medical congresses.
“These data further validate the potential of SPINRAZA as a treatment for patients with SMA,” said B. Lynne Parshall, chief operating officer of Ionis Pharmaceuticals. “We are grateful to all the families and clinicians who have participated in all of the SPINRAZA studies. Without their commitment and support, this program would not have been able to progress so quickly.”
The U.S. Food and Drug Administration (FDA) recently accepted the company’s New Drug Application (NDA) for SPINRAZA as a treatment for SMA and communicated they plan to act early on the NDA under an expedited review. Additionally, the European Medicines Agency (EMA) recently validated Biogen’s Marketing Authorization Application (MAA) in the EU. The EMA’s Committee for Medicinal Products for Human Use (CHMP) granted Accelerated Assessment status and the FDA granted Priority Review to SPINRAZA. Biogen is initiating regulatory filings in other countries in the coming months.
Biogen initiated a global expanded access program (EAP) in infantile-onset SMA earlier this year. The company will continue to explore where and when the EAP may be broadened to include patients with later-onset SMA (consistent with Type 2).
The SPINRAZA Clinical Trial Program
SPINRAZA has been studied in both presymptomatic and symptomatic patients with SMA including patients likely to develop or diagnosed with SMA Types 1, 2, and 3.
The SPINRAZA Phase 3 program is comprised of two registrational studies, ENDEAR and CHERISH. ENDEAR is a thirteen-month study investigating SPINRAZA in 122 patients with infantile-onset SMA, including patients with the onset of signs and symptoms of SMA at up to six months of age. The endpoint pre-specified for the interim analysis of the study evaluated the proportion of motor milestone responders from the motor component of the Hammersmith Infant Neurological Examination (HINE). Given the results of the positive interim analysis, the ENDEAR study is being stopped and participants are able to transition into the SHINE open-label study, in which all patients will receive SPINRAZA.
Additionally, the SHINE open-label extension study for patients who previously participated in ENDEAR or CHERISH is open and is intended to evaluate the long-term safety and tolerability of SPINRAZA.
Two additional Phase 2 studies, EMBRACE and NURTURE, were designed to collect additional data on SPINRAZA. EMBRACE is studying a small subset of patients with infantile or later-onset SMA who do not meet the age and other criteria of ENDEAR or CHERISH. NURTURE is an open-label, ongoing study in pre-symptomatic infants who are up to six weeks of age at time of first dose to determine if treatment before symptoms begin would prevent or delay the onset of SMA symptoms. An interim analysis of NURTURE showed that infants treated for up to one year with SPINRAZA achieved motor milestones in timelines more consistent with normal development than what is observed in the natural history of patients with Type 1 SMA. Three infants experienced adverse events considered possibly related to SPINRAZA, all of which resolved. In addition, no infants have discontinued or withdrawn from the study and no new safety concerns have been identified. NURTURE is currently active and enrolling. All studies are being conducted on a global scale.
About SMA1-5
Spinal Muscular Atrophy (SMA) is characterized by loss of motor neurons in the spinal cord and lower brain stem, resulting in severe and progressive muscular atrophy and weakness. Ultimately, individuals with the most severe type of SMA can become paralyzed and have difficulty performing the basic functions of life, like breathing and swallowing.
Due to a loss of, or defect in the SMN1 gene, people with SMA do not produce enough survival motor neuron (SMN) protein, which is critical for the maintenance of motor neurons. The severity of SMA correlates with the amount of SMN protein. People with Type 1 SMA, the most severe life-threatening form, produce very little SMN protein and do not achieve the ability to sit without support or live beyond 2 years without respiratory support. People with Type 2 and Type 3 produce greater amounts of SMN protein and have less severe, but still life-altering forms of SMA.
Currently, there is no approved treatment for SMA.
To support awareness and education in SMA, Biogen has launched Together in SMA in the United States. Together in SMA is a program created to provide informational materials and resources to the SMA community. Learn more at www.TogetherinSMA.com.
About SPINRAZA (nusinersen)
SPINRAZA is an investigational, potentially disease-modifying therapy for the treatment of SMA that was discovered and developed by Ionis Pharmaceuticals, a leader in antisense therapeutics. SPINRAZA is an antisense oligonucleotide (ASO) that is designed to alter the splicing of SMN2, a gene that is nearly identical to SMN1, in order to increase production of fully functional SMN protein.7
ASOs are short synthetic strings of nucleotides designed to selectively bind to target RNA and regulate gene expression. Through use of this technology, SPINRAZA has the potential to increase the amount of functional SMN protein in infants and children with SMA.
Both the U.S. and EU have granted SPINRAZA Orphan Drug status. Additionally, both the U.S. and EU regulatory agencies have granted special status to SPINRAZA, including Fast Track Designation and Priority Review in the U.S. and Accelerated Assessment in the EU.
Biogen exercised its option to worldwide rights to SPINRAZA in August 2016.
Biogen and Ionis Pharmaceuticals acknowledge support from the following organizations for SPINRAZA: Cure SMA, Muscular Dystrophy Association, and SMA Foundation, intellectual property licensed from Cold Spring Harbor Laboratory and the University of Massachusetts Medical School.
About Biogen
Through cutting-edge science and medicine, Biogen discovers, develops and delivers worldwide innovative therapies for people living with serious neurological, autoimmune and rare diseases. Founded in 1978, Biogen is one of the world’s oldest independent biotechnology companies and patients worldwide benefit from its leading multiple sclerosis and innovative hemophilia therapies. For more information, please visit www.biogen.com. Follow us on Twitter.
About Ionis Pharmaceuticals Inc.
Ionis is the leading company in RNA-targeted drug discovery and development focused on developing drugs for patients who have the highest unmet medical needs, such as those patients with severe and rare diseases. Using its proprietary antisense technology, Ionis has created a large pipeline of first-in-class or best-in-class drugs, with over a dozen drugs in mid- to late-stage development. Drugs currently in Phase 3 development include volanesorsen, a drug Ionis is developing and plans to commercialize through its wholly owned subsidiary, Akcea Therapeutics, to treat patients with either familial chylomicronemia syndrome or familial partial lipodystrophy; IONIS-TTRRx, a drug Ionis is developing with GSK to treat patients with all forms of TTR amyloidosis; and SPINRAZA (nusinersen), a drug Ionis is developing with Biogen to treat infants and children with spinal muscular atrophy. Ionis’ patents provide strong and extensive protection for its drugs and technology. Additional information about Ionis is available at www.ionispharma.com.
Biogen Safe Harbor
This press release contains forward-looking statements, including statements relating to the potential safety and efficacy of SPINRAZA, clinical trial results, potential regulatory approval and the timing thereof, and planning for launch readiness. These statements may be identified by words such as “believe,” “except,” “may,” “plan,” “potential,” “will” and similar expressions, and are based on our current beliefs and expectations. Drug development and commercialization involve a high degree of risk, and only a small number of research and development programs result in commercialization of a product. Factors which could cause actual results to differ materially from our current expectations include: the risk that unexpected concerns may arise from additional data or analysis from our clinical trials; regulatory submissions may take longer or be more difficult to complete than expected; regulatory authorities may require additional information or further studies or may fail to approve or may delay approval of SPINRAZA or grant marketing approval that is different than anticipated; and risks relating to the potential launch of SPINRAZA, including preparedness of healthcare providers to treat patients, the ability to obtain and maintain adequate reimbursement for SPINRAZA and other unexpected difficulties or hurdles. For more detailed information on the risks and uncertainties associated with our drug development and commercialization activities, please review the Risk Factors section of our most recent annual report or quarterly report filed with the Securities and Exchange Commission. Any forward-looking statements speak only as of the date of this press release and we assume no obligation to update any forward-looking statement.
Ionis Forward-looking Statement
This press release includes forward-looking statements regarding Ionis’ strategic relationship with Biogen and the development, activity, therapeutic potential, safety and commercialization of SPINRAZA. Any statement describing Ionis’ goals, expectations, financial or other projections, intentions or beliefs is a forward-looking statement and should be considered an at-risk statement. Such statements are subject to certain risks and uncertainties, particularly those inherent in the process of discovering, developing and commercializing drugs that are safe and effective for use as human therapeutics, and in the endeavor of building a business around such drugs. Ionis’ forward-looking statements also involve assumptions that, if they never materialize or prove correct, could cause its results to differ materially from those expressed or implied by such forward-looking statements. Although Ionis’ forward-looking statements reflect the good faith judgment of its management, these statements are based only on facts and factors currently known by Ionis. As a result, you are cautioned not to rely on these forward-looking statements. These and other risks concerning Ionis’ programs are described in additional detail in Ionis’ annual report on Form 10-K for the year ended December 31, 2015, and its most recent quarterly report on Form 10-Q, which are on file with the SEC. Copies of these and other documents are available from the Company.
BIOGEN and the BIOGEN logo are registered trademarks of BIOGEN. SPINRAZATM is a trademark of BIOGEN.
Ionis Pharmaceuticals™ is a trademark of Ionis Pharmaceuticals, Inc. Akcea Therapeutics™ is a trademark of Ionis Pharmaceuticals, Inc.
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Darras B, Markowitz J, Monani U, De Vivo D. Chapter 8 – Spinal Muscular Atrophies. In: Vivo BTD, ed. Neuromuscular Disorders of Infancy, Childhood, and Adolescence (Second Edition). San Diego: Academic Press; 2015:117-145. |
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Lefebvre S, Burglen L, Reboullet S, et al. Identification and characterization of a spinal muscular atrophy-determining gene. Cell. 1995;80(1):155-165. |
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Mailman MD, Heinz JW, Papp AC, et al. Molecular analysis of spinal muscular atrophy and modification of the phenotype by SMN2. Genet Med. 2002;4(1):20-26. |
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Monani UR, Lorson CL, Parsons DW, et al. A single nucleotide difference that alters splicing patterns distinguishes the SMA gene SMN1 from the copy gene SMN2. Hum Mol Genet. 1999;8(7):1177-1183. |
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Peeters K, Chamova T, Jordanova A. Clinical and genetic diversity of SMN1-negative proximal spinal muscular atrophies. Brain. 2014;137(Pt 11):2879-2896. |
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Rigo F, Hua Y, Krainer AR, Bennett CF. Antisense-based therapy for the treatment of spinal muscular atrophy. J Cell Biol. 2012;199(1):21-25 |
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Hua Y, Sahashi K, Hung G, Rigo F, Passini MA, Bennett CF, Krainer AR. Antisense correction of SMN2 splicing in the CNS rescues necrosis in a type III SMA mouse model. Genes Dev. 2010 Aug 1; 24(15):16344-44 |
Media:
Biogen
Ligia Del Bianco, +1 781-464-3260
public.affairs@biogen.com
or
Ionis Pharmaceuticals
Wade Walke, +1 760-603-2741
CorpComm@ionisph.com
or
Investor:
Biogen
Ben Strain, +781-464-2442
IR@biogen.com
or
Ionis Pharmaceuticals
Wade Walke, +1 760-603-2741
CorpComm@ionisph.com
TEMPE, Ariz. and EDEN PRAIRIE, Minn., Nov. 07, 2016 — Insight Enterprises (Nasdaq:NSIT), an Intelligent Technology Solutions™ provider (“Insight” or “the Company”), and Datalink Corporation (Nasdaq:DTLK), a leading provider of IT services and enterprise data center solutions (“Datalink”), have entered into a definitive merger agreement under which Insight will acquire Datalink for $11.25 per share in cash, representing a 19% premium to Datalink’s closing share price on November 4, 2016. The transaction implies an equity purchase price of approximately $258 million and an enterprise value of approximately $196 million (net of cash and debt acquired).
Datalink is a premier provider of IT services and solutions headquartered near Minneapolis, Minn., with offices in 35 locations in the United States and approximately 570 teammates. Datalink delivers value to Fortune 1000 and public sector clients by providing complete IT solutions that include hardware, software and services to create business impact for their clients.
Insight expects to achieve approximately $20 million in run-rate cost savings within two years after closing, primarily related to corporate efficiencies, duplicative functions and IT system integration. The transaction is expected to be accretive to 2017 adjusted earnings per share (excluding transaction and integration expenses).
“The data center is at the core of our clients’ strategic investments. With the increasing number of options from converged to hyper-converged solutions as well as hybrid cloud options, the landscape has become more complex and clients are looking for help as they evaluate alternatives. The acquisition of Datalink is a significant step in strengthening the foundation of our data center practice as we add the expertise and depth of the Datalink team to our portfolio. We are excited about the combination and look forward to welcoming the Datalink team to our organization,” said Ken Lamneck, CEO of Insight.
“The strength of Datalink’s world-class data center capabilities combined with Insight’s scale and breadth of offerings will bolster our ability to deliver solutions for complex business problems across an expanded footprint of clients. This combination gives our team significant new opportunities to help more organizations elevate and transform their IT,” said Shawn O’Grady, Chief Operating Officer of Datalink.
The combination of the two organizations brings a full complement of end-to-end technology solutions in supply chain, application and data center architecture, implementation and managed solutions. “Our clients, partners and teammates will experience exciting opportunities for growth and development as a result of this acquisition,” said Steve Dodenhoff, president of Insight’s US business.
“Our decision to join forces with Insight is based on our shared commitment to deliver best in class technology, operations and services to meet our clients’ need for IT transformation. Our enterprise solutions platform, sophisticated offerings, talented professionals and our client base will bring a rich dimension to the Insight organization,” said Paul Lidsky, CEO of Datalink.
Terms and Financing
The transaction is subject to certain closing conditions, including regulatory approvals and approval of Datalink’s shareholders, and is expected to close in the first quarter of 2017.
Insight intends to finance the transaction through a combination of cash on hand and borrowings under its existing revolving credit facilities.
Advisors
J.P. Morgan Securities LLC is acting as financial advisor to Insight. Insight’s legal advisor is Sullivan & Cromwell LLP.
Raymond James & Associates is acting as financial advisor and Faegre Baker Daniels LLP is acting as legal advisor to Datalink.
Conference Call
Insight will host a conference call and webcast today, November 7, at 8:30 a.m. ET to discuss the transaction.
The live conference call is available by dialing (877) 402-8904 from the U.S. or (678) 809-1029 from outside the U.S. and entering conference code 3625042. Supporting materials, as well as a link to an audio webcast of the conference call, will be available at http://nsit.client.shareholder.com/index.cfm.
A replay of the conference call will be available for a limited time beginning approximately one hour after completion of the conference call and can be accessed via the Insight website at http://nsit.client.shareholder.com/index.cfm.
Forward Looking Statements
Cautionary Note Regarding Forward-Looking Statements
Certain statements contained in this communication may constitute “forward-looking statements.” Forward-looking statements can usually be identified by the use of words such as “aim,” “anticipate,” “believe,” “continue,” “could,” “estimate,” “evolve,” “expect,” “forecast,” “intend,” “looking ahead,” “may,” “opinion,” “plan,” “possible,” “potential,” “project,” “should,” “will” and other expressions which indicate future events or trends.
These forward-looking statements are based upon certain expectations and assumptions and are subject to risks and uncertainties. Actual results could differ materially from those anticipated as a result of various factors, including the following: Datalink’s shareholders may not approve the transaction; conditions to the closing of the transaction, including receipt of required regulatory approvals, may not be satisfied; the transaction may involve unexpected costs, liabilities or delays; the parties may be unable to achieve expected synergies and operating efficiencies in the merger within the expected time frames or at all and to successfully integrate Datalink’s operations into those of Insight; such integration may be more difficult, time consuming or costly than expected; revenues following the transaction may be lower than expected; operating costs, customer loss and business disruption (including, without limitation, difficulties in maintaining relationships with employees, customers, clients or suppliers) may be greater than expected following the transaction; uncertainties surrounding the transaction; the outcome of any legal proceedings related to the transaction; Datalink and/or Insight may be adversely affected by other economic, business, and/or competitive factors; risks that the pending transaction disrupts current plans and operations; the retention of key employees of Datalink; other risks to consummation of the transaction, including circumstances that could give rise to the termination of the merger agreement and the risk that the transaction will not be consummated within the expected time period or at all; and the other risks described from time to time in Datalink’s and Insight’s reports filed with the Securities and Exchange Commission (the “SEC”) under the heading “Risk Factors,” including each company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2015, subsequent Quarterly Reports on Form 10-Q and in other of Datalink’s and Insight’s filings with the SEC.
All forward-looking statements are qualified by, and should be considered in conjunction with, such cautionary statements. Readers are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date on which such statements were made. Except as required by applicable law, neither Insight nor Datalink undertakes any obligation to update forward-looking statements to reflect events or circumstances arising after such date.
Additional Information and Where to Find It
In connection with the transaction, Datalink intends to file relevant materials with the SEC, including a proxy statement on Schedule 14A. Following the filing of the definitive proxy statement with the SEC, Datalink will mail the definitive proxy statement and a proxy card to each shareholder entitled to vote at the special meeting relating to the transaction. Datalink shareholders are urged to carefully read these materials (and any amendments or supplements) and any other relevant documents that Datalink files with the SEC when they become available because they will contain important information. The definitive proxy statement, the preliminary proxy statement and other relevant materials in connection with the transaction (when they become available), and any other documents filed by Datalink with the SEC, may be obtained free of charge at the SEC’s website (http://www.sec.gov), at Datalink’s investor website (http://www.datalink.com/Investor-Information), or by writing or calling Datalink at Datalink Corporation, 10050 Crosstown Circle, Suite 500, Eden Prairie, Minnesota 55344 or by (952) 944-3462.
Participants in the Solicitation
Datalink and its directors and executive officers, and Insight and its directors and officers, may be deemed to be participants in the solicitation of proxies from Datalink’s stockholders with respect to the transaction. Information about Datalink’s directors and executive officers and their ownership of Datalink’s common stock is set forth in Datalink’s proxy statement on Schedule 14A filed with the SEC on April 15, 2016. To the extent that holdings of Datalink’s securities have changed since the amounts printed in Datalink’s proxy statement, such changes have been or will be reflected on Statements of Change in Ownership on Form 4 filed with the SEC. Information regarding the identity of the participants in the proxy solicitation, and their direct or indirect interests in the transaction, by security holdings or otherwise, will be set forth in the proxy statement and other materials to be filed with SEC in connection with the transaction. Information about the directors and executive officers of Insight is set forth in the proxy statement for Insight’s 2016 Annual Meeting of Stockholders, which was filed with the SEC on April 5, 2016.
About Datalink
Datalink is a complete IT services and solutions provider that helps companies transform their technology, operations, and service delivery to meet business challenges. Combining extensive experience, a full lifecycle of services and a comprehensive approach to producing IT innovations that empower positive business outcomes, Datalink delivers success across cloud IT transformation, next generation technology, and security. For more information, call 800.448.6314 or visit www.datalink.com.
About Insight
From business and government organizations to healthcare and educational institutions, Insight empowers clients with “Intelligent Technology™” solutions to realize their goals. As a Fortune 500-ranked global provider of hardware, software, cloud and service solutions, our 5,700 teammates provide clients the guidance and expertise needed to select, implement and manage complex technology solutions to drive business outcomes. Through our world-class people, partnerships, services and delivery solutions, we help businesses run smarter. Discover more at insight.com . NSIT-F

INSIGHT CONTACTS: INVESTORS:
HELEN JOHNSON
Insight Enterprises
TEL. (480) 333-3234
EMAIL: HELEN.JOHNSON@INSIGHT.COM
MEDIA:
AMY PROTEXTER
Insight Enterprises
TEL. (480) 409-6710
EMAIL: AMY.PROTEXTER@INSIGHT.COM
ARIEL KOUVARAS
Sloane & Company
TEL. (212) 446-1884
EMAIL: akouvaras@sloanepr.com
DATALINK CONTACTS: INVESTORS:
GREG BARNUM
Datalink Corporation
TEL. (952) 279-4816
EMAIL: Gbarnum@Datalink.Com
MEDIA:
MATT SULLIVAN
Padilla CRT
TEL. (612) 455-1709
EMAIL: MATT.SULLIVAN@PADILLACRT.COM
Lead Recycling Process Also Given Special Mention by ICIS for Best Process Innovation Award
ALAMEDA, Calif., Nov. 04, 2016 — Aqua Metals (NASDAQ:AQMS), which is commercializing a non-polluting electrochemical lead recycling technology called AquaRefining™, today announced that it was named the winner of the Sustainable Technology Award in the 2016 IChemE awards program. The company has also received a special mention by ICIS in the Best Process Innovation award category. Both awards recognize the company’s AquaRefining process, which has the potential to revolutionize the lead recycling industry through producing ultra-pure lead with a fundamentally non-polluting, water-based, room temperature process.
“To be honored by two leaders in the chemical engineering industry in such a short time brings attention to the magnitude of the changes we intend to make in the way lead is processed,” said Dr. Stephen R. Clarke, chairman and CEO.
The IChemE awards are presented by the Institution of Chemical Engineers. The IChemE aims to recognize organizations who are raising the bar in the field by improving the practices and applications of chemical engineering. The organization has recognized Aqua Metals for its innovation and sustainability efforts in transforming the way lead is recycled.
The ICIS Innovation Award aims to recognize companies and individuals who have shown innovation in chemical products and processes. They take into consideration the way the innovations benefit the environment and lead the way towards sustainability. The organization gave special mention to Aqua Metals for taking significant technological and business steps toward making AquaRefining a tangible reality in 2016.
The first AquaRefinery located in the Tahoe-Reno Industrial Center (TRIC) in Nevada was built in less than 18 months after the company went public in July 2015 and recently produced the first AquaRefined lead. Aqua Metals is partnering with key companies in the industry, including Interstate Batteries and Battery Systems International, to supply spent lead acid battery cores to the first AquaRefinery.
About Aqua Metals, Inc.
Aqua Metals (NASDAQ:AQMS) is reinventing lead recycling with its patent-pending AquaRefiningTM technology. Unlike smelting, AquaRefining is a room temperature, water-based process that is fundamentally non-polluting. These modular systems are expected to allow the lead-acid battery industry to simultaneously improve environmental impact and scale production to meet rapidly growing demand. Aqua Metals is based in Alameda, California and built its first recycling facility in Nevada’s Tahoe-Reno Industrial Center. To learn more, please visit www.aquametals.com.
Safe Harbor
This press release contains forward-looking statements concerning Aqua Metals, Inc., the lead-acid battery recycling industry, the intended benefits of its agreements with Interstate Batteries, the future of lead-acid battery recycling via traditional smelters, the Company’s development of its commercial lead-acid battery recycling facilities and the quality, efficiency and profitability of Aqua Metals’ proposed lead-acid battery recycling operations. Those forward-looking statements involve known and unknown risks, uncertainties and other factors that could cause actual results to differ materially. Among those factors are: (1) the fact that Company has only recently commenced lead producing operations, thus subjecting the Company to all of the risks inherent in a pre-revenue start-up; (2) the uncertainties involved in any new commercial relationship and the risk that Aqua Metals will not receive the intended benefits of its agreements with Interstate Batteries; (3) risks related to Aqua Metals’ ability to raise sufficient capital, as and when needed, to develop and operate its recycling facilities; (4) changes in the federal, state and foreign laws regulating the recycling of lead-acid batteries; (5) the Company’s ability to protect its proprietary technology, trade secrets and know-how and (6) those other risks disclosed in the section “Risk Factors” included in the Annual Report on Form 10-K filed with the SEC on March 28, 2016. Aqua Metals cautions readers not to place undue reliance on any forward-looking statements. The Company does not undertake, and specifically disclaims any obligation, to update or revise such statements to reflect new circumstances or unanticipated events as they occur.

Media Relations:
Antenna
Brigit Carlson
201-465-8031
brigit@antennagroup.com
www.antennagroup.com
Investor Relations:
MZ North America
Greg Falesnik
949-385-6449
greg.falesnik@mzgroup.us
www.mzgroup.us
ORLANDO, FL–(November 04, 2016) – The trend towards increasing adoption of SPD-Smart electronically dimmable windows (EDWs) for aircraft was evident at this week’s National Business Aviation Association Convention and Exhibition in Orlando, Florida. Aircraft at the show’s static display, mockups on the show floor, and public statements in the media, all point towards the industry’s growing recognition of EDWs as a mature solution for the challenges inherent in controlling light, glare, heat and noise in aircraft cabins.
Business aviation and commercial aviation share the goal of improving the passenger experience, and this need has opened new horizons in cabin innovations. One such innovation is SPD EDW systems. Passengers, at the touch of a button, can instantly and precisely control the amount of daylight and glare coming through their window. They continue to enjoy views by tinting their SPD-Smart EDW to control the amount of light to a comfortable level, rather than blocking their view with a shade. SPD EDW systems offer the aerospace industry a potent and unique solution to improving how passengers feel while in flight, by managing the ideal level of daylight in the cabin — as well as offering a cooler, quieter cabin.
Textron Beechcraft: King Air 350i, King Air 250, and King Air C90GTx
SPD-Smart EDWs, supplied by Research Frontiers licensee InspecTech Aero Service, are standard equipment on all three models of Beechcraft King Airs: King Air 350i, King Air 250, and King Air C90GTx. Two models of King Airs were at this week’s NBAA show. InspecTech is now shipping their “iShade” brand of SPD-Smart EDWs for all three models, and King Airs with the new interiors are now being delivered to customers.
Honda Aircraft Company: HondaJet HA-420
SPD-Smart EDWs, supplied by Research Frontiers licensee Vision Systems, are standard equipment on the HondaJet HA-420. A HondaJet demonstrator aircraft was on display at this week’s NBAA show. Vision Systems is now shipping their “Nuance” brand of SPD-Smart EDWs for the HondaJet. Deliveries of the HondaJet to customers began in December of 2015.
Dassault Aviation: Falcon 5X
SPD-Smart skylights, supplied by Vision Systems, have been selected as standard equipment on the upcoming Dassault Falcon 5X. At this week’s NBAA, a mockup of this aircraft was on display. To offer business aviation’s first skylight, Dassault was faced with a critical need to manage the intense solar light, glare and heat coming into the cabin, and SPD-Smart EDW technology provide the solution. At the NBAA, the media reported that Dassault is confident that the Falcon 5X will be ready for service entry in 2020.
Bell Helicopter: 525 and 429 VIP helicopters
SPD-Smart EDWs are offered on the Bell Helicopter 429 VIP. Deliveries of this model, with the new interior, was announced by Bell as beginning in March of this year. Passengers control the SPD-Smart EDWs using their own smart devices, which connect to the internal Wi-Fi in the aircraft. SPD-Smart EDWs are also to be offered on the upcoming VIP Model 525. Bell hopes to certify this super-medium rotorcraft in late 2017 or early 2018. At this week’s NBAA, this model, with SPD-Smart EDWs, was launched at the booth of Bell Helicopter.
Epic Aircraft: E1000
At this week’s NBAA, a mockup of the Epic E1000 aircraft, with SPD-Smart EDWs, was exhibited. EDWs are standard equipment on the upcoming E1000 — the company now expects that certification is expected in the summer of 2017, with deliveries to begin shortly thereafter. The status of the E1000 was covered by the media at the show: here is an example. The E1000 uses carbon fiber composite material in the airframe, and as a result larger, and a greater number, of passenger windows are possible. These windows presented a light, glare and heat challenge, however SPD-Smart technology provides the elegant solution.
Survey on EDWs replacing window shades
Further evidence of the industry’s growing recognition of EDWs as a mature solution for the challenges inherent in controlling light, glare, heat and noise in aircraft cabins can be seen in a recent survey. The publication Business Jet Interiors International recently conducted a survey with the question: “Will ‘smart’ glass ever fully replace window shades?” 69% of respondents indicated “Yes.”
Lufthansa Technik and Mercedes interior for VIP aircraft
At the NBAA this week, an example of the industry’s movement towards EDWs as a solution to a myriad of cabin comfort challenges was Lufthansa Technik and Mercedes presenting the final version of their next-generation interior design for private jets having the size of Airbus and Boeing aircraft. The early design concept, revealed in 2015, has evolved to meet the requirements of airworthiness and certification. A unique use of EDWs are under evaluation for this interior, and the EDW feature has been widely reported in the media: here is an example.
Airbus Corporate Jets: Melody interior
Another example of the trend towards EDW adoption was seen this week in NBAA show media reports about Airbus Corporate Jet’s “Melody” cabin concept, for future customers of the ACJ320neo family of aircraft. These reports indicate inclusion of EDWs that can control the amount of natural light entering the cabin. Please read this article for an example.
Vision Systems at 2016 NBAA
Vision Systems showcased an array of SPD-Smart EDWs at NBAA, including its new “Acti-Vision” product which incorporates an interactive transparent display in the EDW, products that combine SPD EDWs with traditional shades, and EDW solutions for the cockpit. The media covered Vision Systems at the show, and here is an example (go to page 10).
The comfort and benefits an SPD-Smart EDW system delivers extends to all passengers. Cabin-wide control, operated either automatically with photosensors, or manually by the crew, can result in the optimum level of daylight present throughout the cabin at all times. Benefits include greater daylighting, enhanced views, and a more open feeling resulting in greater perceived space. The management and “harvesting” of healthy daylighting instantly transforms the cabin, and synergistically complements other cabin systems including interior mood lighting systems and entertainment systems, for an unequalled passenger experience.
Aircraft windows are a primary path of other environmental elements entering an aircraft cabin through the window opening — heat and noise. These unwanted elements — cabin heat while the aircraft is at the gate or on the taxiway, and cabin noise during the entire flight — are well known to cause passengers discomfort, fatigue, jet lag and other physical and psychological ailments. SPD EDW systems provide remarkable thermal and acoustic insulation, further improving the passenger experience for all. Coupled with the superior daylight management benefits, as an integrated system it is the complete solution for managing the environmental challenges outside conditions inflict on the cabin interior.
About Research Frontiers Inc.
Research Frontiers (NASDAQ: REFR) is the developer of SPD-Smart light-control technology which allows users to instantly, precisely and uniformly control the shading of glass or plastic, either manually or automatically. Research Frontiers has built an infrastructure of over 40 licensed companies that collectively are capable of serving the growing global demand for smart glass products in automobiles, homes, buildings, museums, aircraft and boats. For more information, please visit our website at www.SmartGlass.com, and on Facebook, Twitter, LinkedIn and YouTube.
Note: From time to time Research Frontiers may issue forward-looking statements which involve risks and uncertainties. This press release contains forward-looking statements. Actual results could differ and are not guaranteed. Any forward-looking statements should be considered accordingly. “SPD-Smart” is a trademark of Research Frontiers Inc. “iShade” is a trademark of InspecTech Aero Service. “Nuance” is a trademark of Vision Systems.
For further information about SPD-Smart light-control technology, please contact:
Michael R. LaPointe
Vice President
Aerospace Products
Research Frontiers Inc.
+1-516-364-1902
Info@SmartGlass.com
Cytori Therapeutics, Inc. (NASDAQ: CYTX) will present new preclinical data describing positive effects of Cytori Cell Therapy™ on a corneal wound healing model and in cutaneous scarring following burn injury. The data will be presented at the International Federation for Adipose Therapeutics (IFATS) in San Diego on November 17-20, 2016.
One presentation is titled “Adipose-Derived Regenerative Cells Promote Proliferation of Corneal Epithelial Cell And Corneal Wound Healing.” This presentation will focus on the effects of Cytori Cell Therapy on corneal wound healing using cell culture and corneal explant culture models. The cornea is particularly sensitive to injury following exposure to chemical agents and there is an unmet need for therapies capable of promoting corneal healing following accidental or terrorist-initiated exposure to chemical agents.
Another presentation is titled “Autologous Adipose Derived Regenerative Cell (ADRCs) Therapy For The Prevention And Treatment Of Hypertrophic Scars Using A Red Duroc Porcine Model,” which suggests the ability of Cytori’s DCCT-10 cell therapy to mitigate the development of hypertrophic scarring in a porcine model.
This research was funded by Cytori’s contract with the Biomedical Advanced Research and Development Authority of the U.S. Department of Health and Human Services (HHSO100201200008C).
About Cytori Therapeutics, Inc.
Cytori Therapeutics is a late stage cell therapy company developing autologous cell therapies from adipose tissue to treat a variety of medical conditions. Data from preclinical studies and clinical trials suggest that Cytori Cell Therapy™ acts principally by improving blood flow, modulating the immune system, and facilitating wound repair. As a result, Cytori Cell Therapy™ may provide benefits across multiple disease states and can be made available to the physician and patient at the point-of-care through Cytori’s proprietary technologies and products. For more information, visit www.cytori.com.
Cautionary Statement Regarding Forward-Looking Statements
This press release includes forward-looking statements regarding events, trends, and/or business prospects, which may affect our future operating results and financial position. Such statements, including statements regarding potential benefits of use of topical or intravenous administration of Cytori Cell Therapy in corneal wound and burn patients (including for wound healing and reduction of hypertrophic scarring), are subject to risks and uncertainties that could cause our actual results and financial position to differ materially. These risks and uncertainties include preclinical, clinical and regulatory uncertainties, such as risks in the collection and results of preclinical data, risks that any proposed clinical trials regarding wound and scar healing are not approved or funded, risks that BARDA may lose the ability to keep funding Cytori’s clinical studies, or may elect to discontinue its funding of Cytori’s work, unfavorable results of any clinical studies or trials using Cytori Cell Therapy, final clinical outcomes, and other risks and uncertainties described under the “Risk Factors” in Cytori’s Securities and Exchange Commission Filings, included in our annual and quarterly reports. There may be events in the future that we are unable to predict, or over which we have no control, and our business, financial condition, results of operations and prospects may change in the future. We assume no responsibility to update or revise any forward-looking statements to reflect events, trends or circumstances after the date they are made unless we have an obligation under U.S. Federal securities laws to do so.

Cytori Therapeutics, Inc.
Tiago Girao, +1 858-458-0900
ir@cytori.com
— Nestlé Health Science to Make Investment through the Purchase of Nearly 7.6 Million Shares of Aimmune Stock at $19.20 per Share —
— Companies Enter into Strategic Collaboration Agreement Designed to Enable the Successful Development and Commercialization of Innovative Food Allergy Therapies —
— Nestlé Health Science CEO Greg Behar Will Join Aimmune Board of Directors —
— Aimmune Retains All Current and Future CODIT™ Pipeline Assets —
— Aimmune Management to Host Conference Call Today at 8 a.m. ET / 5 a.m. PT —
Aimmune Therapeutics, Inc. (Nasdaq:AIMT), a biopharmaceutical company developing CODIT™ (Characterized Oral Desensitization ImmunoTherapy), an approach to treating life-threatening food allergies, today announced that Nestlé Health Science will make a $145.0 million equity investment in Aimmune. Aimmune and Nestlé Health Science also entered into a strategic collaboration agreement designed to enable the successful development and commercialization of innovative food allergy therapies. Aimmune will retain all current and future pipeline assets developed with the CODIT approach, including AR101, the company’s investigational oral biologic desensitization therapy for peanut allergy, which is currently in Phase 3 clinical development.
“We are extremely pleased that Nestlé Health Science, a global leader in food allergy management, is making this investment in Aimmune, as it reflects our shared commitment to reducing the risk and burden of food allergies affecting millions of people worldwide,” said Aimmune CEO Stephen Dilly, M.B.B.S., Ph.D. “This significant investment will put us in a strong cash position of more than $300 million and enables important additional pipeline advancement activities beyond AR101 for peanut allergy.
“Nestlé Health Science is an ideal partner that brings a shared vision, global scale and complementary capabilities to this collaboration, making the whole more than the sum of the parts,” continued Dr. Dilly. “We are excited to have Nestlé Health Science alongside as we pursue our development plans and seek to realize the full promise of our CODIT approach by addressing the important questions in food allergy around optimizing treatments, achieving sustained unresponsiveness, and exploring the science around tolerance.”
Greg Behar, CEO of Nestlé Health Science, who will join the Aimmune Board, stated: “Food allergies have a huge personal impact and are a health economic burden. Nestlé Health Science is investing and innovating to change the approach to food allergy management, with integrated approaches from diagnostics (Dx) to nutrition solutions (Nx) and now biologics (Rx), where Aimmune’s proprietary approach has transformational potential in the lives of patients and families.”
Upon closing of the equity investment, Aimmune will receive a payment of $145.0 million in connection with Nestlé Health Science’s purchase of 7,552,084 newly issued shares of Aimmune’s common stock at $19.20 per share, which corresponds to a 15 percent stake after the completion of the transaction. The investment and the collaboration do not include any development milestones, product marketing rights or royalties.
The investment launches a two-year strategic collaboration between Nestlé Health Science and Aimmune, the terms of which enable the parties to engage on Aimmune’s current and future oral immunotherapy development programs through a newly established pipeline forum. Nestlé Health Science will provide ongoing scientific, regulatory, and commercial expertise and advice to Aimmune through the pipeline forum. Any information disclosed in the collaboration will remain the confidential information of Aimmune, and any new ideas or inventions that arise that relate to Aimmune products will be the solely owned intellectual property of Aimmune. If Aimmune elects to seek a partner or collaborator for one of its oral immunotherapy development programs during the two-year term of the collaboration, Nestlé Health Science will have a three-month period to negotiate exclusively with Aimmune.
This transaction has been approved by the boards of directors of both companies. The companies expect to close the equity investment by the end of 2016, subject to the expiration or termination of applicable waiting periods under all applicable antitrust laws and satisfaction of other usual and customary closing conditions.
Conference Call and Webcast Information
Aimmune will host a conference call and live audio webcast Friday, November 4, 2016, at 8 a.m. ET / 5 a.m. PT to discuss the announced Nestlé Health Science investment and collaboration. The conference call will be accessible via the company’s website at www.aimmune.com on the Events page under Investor Relations. Please connect to the company’s website at least 15 minutes prior to the start of the conference call to ensure adequate time for any software download that may be required to listen to the webcast. Alternatively, participants may dial 1-877-497-1438 (domestic) or 1-262-558-6296 (international) and refer to conference ID 14236792. An archived copy of the webcast will be available on the company’s website for at least 30 days after the conference call. Alternatively, a replay of the call can be accessed by dialing 1-855-859-2056 (domestic) or 1-404-537-3406 (international) and referring to conference ID 14236792. The replay of the call will be available for approximately two business days following the live call.
About Aimmune Therapeutics
Aimmune Therapeutics, Inc., is a clinical-stage biopharmaceutical company developing treatments for life-threatening food allergies. The company’s Characterized Oral Desensitization ImmunoTherapy (CODIT™) approach is intended to achieve meaningful levels of protection by desensitizing patients with defined, precise amounts of key allergens. Aimmune’s first investigational product using CODIT™, AR101 for the treatment of peanut allergy, has received the FDA’s Breakthrough Therapy Designation for the desensitization of peanut-allergic patients 4-17 years of age and is currently being evaluated in Phase 3 clinical trials in ages 4-55. AR101 is a characterized, regulated, oral biological drug product containing the protein profile found in peanuts. For more information, please see www.aimmune.com.
About Nestlé Health Science
Nestlé Health Science, a wholly-owned subsidiary of Nestlé, is a health-science company engaged in advancing the role of nutritional therapy to change the course of health for consumers, patients and its partners in healthcare. Nestlé Health Science’s portfolio of nutrition solutions, diagnostics, devices and drugs, targets a number of health areas, such as inborn errors of metabolism, pediatric and acute care, obesity care, healthy aging as well as gastrointestinal and brain health. Through investing in innovation and leveraging leading edge science, Nestlé Health Science employs around 3,000 people worldwide and is headquartered in Epalinges (near Lausanne), Switzerland. For more information, please visit: www.nestlehealthscience.com.
Forward-Looking Statements
Statements contained in this press release regarding matters that are not historical facts are “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995. Because such statements are subject to risks and uncertainties, actual results may differ materially from those expressed or implied by such forward-looking statements. Such statements include, but are not limited to, statements regarding: Aimmune’s expectations that the $145.0 million equity financing from Nestlé Health Science will close in 2016; Aimmune’s expectations that its cash position after the closing of the equity financing from Nestlé Health Science will be more than $300 million; Aimmune’s expectations that Greg Behar will join Aimmune’s Board of Directors after the closing of the financing from Nestlé Health Science; Aimmune’s expectations that the additional cash received from the equity financing will enable it to conduct additional pipeline advancement activities; Aimmune’s expectations that the collaboration with Nestlé Health Science will help enable the successful development and commercialization of innovative food allergy therapies; and Aimmune’s expectations regarding potential applications of the CODIT™ approach to treating life-threatening food allergies. Risks and uncertainties that contribute to the uncertain nature of the forward-looking statements include: the expectation that Aimmune will need additional funds to finance its operations; the company’s ability to initiate and/or complete clinical trials; the unpredictability of the regulatory process; the possibility that Aimmune’s clinical trials will not be successful; Aimmune’s dependence on the success of AR101; the company’s reliance on third parties for the manufacture of the company’s product candidates; possible regulatory developments in the United States and foreign countries; and the company’s ability to attract and retain senior management personnel. These and other risks and uncertainties are described more fully in Aimmune’s most recent filings with the Securities and Exchange Commission, including its Annual Report on Form 10-K for the year ended 2015 and Quarterly Report on Form 10-Q for the quarter ended June 30, 2016. All forward-looking statements contained in this press release speak only as of the date on which they were made. Aimmune undertakes no obligation to update such statements to reflect events that occur or circumstances that exist after the date on which they were made.
This press release concerns a product that is under clinical investigation and that has not yet been approved for marketing by the U.S. Food and Drug Administration (FDA) or the European Medicines Agency (EMA). It is currently limited to investigational use, and no representation is made as to its safety or effectiveness for the purposes for which it is being investigated.
Clinical Data from Phase 1 SAD Trials of MYK-461 in Hypertrophic Cardiomyopathy Patients and Healthy Volunteers
New Animal Model Research Advances Understanding of HCM Pathophysiology
SOUTH SAN FRANCISCO, Calif., Nov. 04, 2016 — MyoKardia, Inc. (Nasdaq:MYOK), a clinical stage biopharmaceutical company pioneering a precision medicine approach for the treatment of heritable cardiovascular diseases, today announced presentations at American Heart Association (AHA) Scientific Sessions 2016 highlighting the Company’s clinical and animal model research in hypertrophic cardiomyopathy (HCM), novel insights from its SHaRe registry and precision cardiovascular approach, as well as two of MyoKardia’s cofounders presenting research in understanding HCM causes and outcomes. AHA Scientific Sessions 2016 will be held Nov. 12-16 in New Orleans.
Clinical Data from Phase 1 SAD Trials of MYK-461 in Hypertrophic Cardiomyopathy
Data from MyoKardia’s two Phase 1 single ascending dose trials of MYK-461 in HCM patients and healthy volunteers will be presented by Martin S. Maron, M.D., Director of the Hypertrophic Cardiomyopathy Center at Tufts Medical Center in Boston. Topline data from the studies were released in July 2016.
The studies were designed to establish the safety and tolerability of single oral doses of MYK-461. Secondary objectives included establishing the preliminary pharmacokinetic and pharmacodynamics profiles of MYK-461. Clinical proof of mechanism was observed overall as a dose-dependent reduction in cardiac contractility following single oral doses, in both healthy volunteers and HCM patients.
MyoKardia is currently studying MYK-461 in PIONEER-HCM, a Phase 2 open-label single-arm pilot study to evaluate safety, tolerability and efficacy of MYK-461 in subjects with symptomatic, obstructive HCM (oHCM). The U.S. Food and Drug Administration has granted the company Orphan Drug Designation for MYK-461 for the treatment of symptomatic oHCM.
The poster presentation, “Obstructive Hypertrophic Cardiomyopathy: Initial Single Ascending Dose Data in Healthy Volunteers and Patients,” is part of the “Hypertrophic Cardiomyopathy: New Insights” session. The presentation is on Nov. 15, 10:45 AM to 12:00 PM, in the Science and Technology Hall, Clinical Science Section.
New Animal Model Data Advances Understanding of HCM Pathophysiology
Previous MyoKardia research, including results published in a recent paper in the leading medical journal Science, has provided evidence of the ability of MYK-461 to prevent and reverse development of HCM in multiple animal models. A new study highlighted at AHA sheds further light on how mutations in sarcomere genes lead to the physiology of HCM. The findings of the MyoKardia study provide the first evidence integrating molecular, cellular and organ-level studies that hypercontractility, subclinical ischemia and fibrosis contribute to the early pathogenesis of HCM.
Ferhaan Ahmad, M.D., Ph.D., Director of the Cardiovascular Genetics Program at the University of Iowa, will present “A Minipig Genetic Model of Hypertrophic Cardiomyopathy.” The presentation is part of the “Molecular Basis of Cardiac Hypertrophy” session on Nov. 15, from 1:30 to 2:45 PM, and is being held in the Science and Technology Hall, Clinical Science Section.
The experiments highlighted by Dr. Ahmad were performed on proprietary genetic pig models of HCM, which were created by Exemplar Genetics, a wholly-owned subsidiary of Intrexon Corporation. MyoKardia and Exemplar Genetics have formed a multi-year collaboration, in which MyoKardia may direct the development of additional pig models of disease by Exemplar Genetics, each with distinct genetic defects known to cause heritable cardiomyopathies. Researchers anticipate this model, and future models created under the collaboration, will be valuable for advancing our understanding of disease pathophysiology and for the further development of novel therapeutics to treat heritable cardiomyopathies.
Presentations Highlight SHaRe, Precision Medicine
- Eric Green, M.D., Ph.D., senior director of translational research at MyoKardia, will present “Translating Insights from Human Genetics into Precision Therapeutics” during the “Precision Medicine 2016: Changing Genetic Destiny: New Approaches to Therapy” session at AHA. The presentation is scheduled for Nov. 14, 2:30 to 2:45 PM.
- A discussion of HCM databases that includes the Sarcomeric Human Cardiomyopathy Registry, or SHaRe, will be included in the “Genotype-Phenotype Correlations: Identification and Prevention” presentation at AHA. The presentation, part of the “Precision to Population: Optimizing Outcomes in HF” session, will be delivered by Carolyn Ho, M.D., Associate Professor, Harvard Medical School. It is scheduled for Nov. 15, 11:00 to 11:15 AM.
MyoKardia Co-Founders Leslie Leinwand and Christine Seidman Present Research on Cardiomyopathy Causes and Outcomes
- MyoKardia co-founders Leslie Leinwand, Ph.D., Molecular, Cellular, and Developmental Biology Professor and the chief scientific officer of the BioFrontiers Institute at the University of Colorado, Boulder; and Christine Seidman, M.D., a professor of genetics and the Thomas W. Smith professor of medicine at Harvard Medical School and Brigham and Women’s Hospital, will each be presenting in separate sessions at AHA.
- Dr. Leinwand will present “Functional Changes in Motor and Structural Proteins Causing HCM” during the “Cellular and Molecular Aspects of Hypertrophic Cardiomyopathy” session, which focuses on the latest research in cellular and molecular aspects of HCM. The presentation is Nov. 15, 10:45 to 11:00 AM.
- Dr. Seidman will present “Genomics and Heart Failure: The Secret Within,” at AHA. The presentation is part of a session entitled “From Precision to Population: Optimizing Outcomes in HF,” that focuses on the role of precision medicine in heart failure. It is scheduled for Nov. 15, 10:45 to 11:00 AM.
About MYK-461 and PIONEER-HCM
MYK-461 is an orally administered small molecule designed to reduce left ventricular contractility by allosterically modulating the function of cardiac myosin, the motor protein that drives heart muscle contraction. MyoKardia has evaluated MYK-461 in three Phase 1 clinical trials, primarily designed to evaluate safety and tolerability of oral doses of MYK-461, as well as provide pharmacokinetic and pharmacodynamic data. In April 2016, the U.S. FDA granted the company Orphan Drug Designation for MYK-461 for the treatment of symptomatic oHCM, a subset of HCM.
MyoKardia is currently studying MYK-461 in PIONEER-HCM, a Phase 2 open-label single-arm pilot study to evaluate safety, tolerability and efficacy of MYK-461 in patients with symptomatic oHCM. The primary endpoint of PIONEER-HCM is the level of reduction in post-exercise left ventricular outflow tract (LVOT) gradient over 12 weeks of drug treatment. PIONEER-HCM will also explore the relationship between reduction in contractility and LVOT gradient, endpoints measuring functional capacity (i.e., exercise) and clinical symptoms in addition to gathering safety and tolerability data on MYK-461 in an outpatient setting.
About HCM and oHCM
It is estimated that one in every 500 people in the United States has HCM, the most prevalent form of heritable cardiomyopathy. HCM is defined as an otherwise unexplained thickening of the walls of the heart, known as hypertrophy. The consequences include reduced left ventricular volumes and cardiac output, reduced ability of the left ventricle to expand, and elevated filling pressures. These can all contribute to reduced effort tolerance and symptoms that include shortness of breath and chest pain. HCM is a chronic disease and for the majority of patients, the disease progresses slowly and can be extremely disabling. HCM substantially increases the risk of developing atrial fibrillation that can lead to stroke or malignant ventricular arrhythmias that can cause sudden cardiac death. There are currently no approved drug products indicated for the treatment of HCM. Patients are typically prescribed one or more drugs (including beta blockers, non-dihydropyridine calcium channel blockers and disopyramide) indicated for the treatment of hypertension, heart failure or other cardiovascular disorders more generally.
oHCM is a physiological complication of HCM in which the thickened heart muscle obstructs the LVOT. Approximately two thirds of all HCM patients have obstruction, either at rest or with provocation like exercise. Measured most commonly by non-invasive imaging (echocardiography), oHCM is defined as ≥30 mm Hg pressure gradient across the LVOT. Symptoms of oHCM can include shortness of breath, chest pain, dizziness, fainting, and palpitations. The presence of obstruction in an HCM patient further increases risk of progression to severe symptoms, and risk of death from heart failure or stroke.
The degree of LVOT obstruction in oHCM patients is a primary criterion for surgical and other invasive interventions (recommended for symptomatic patients with LVOT gradients measured at ≥50 mmHg). Relief of obstruction has been associated with improved symptoms, function and clinical outcomes. Surgical or other invasive interventions, including septal myectomy, an open heart procedure, may be appropriate. There are no approved drug products indicated for this condition. The primary endpoint of the Phase 2 PIONEER-HCM study is to assess level of reduction in LVOT gradient over 12 weeks of drug treatment. The trial is also exploring relationships among reductions in contractility, LVOT gradient and endpoints that include safety, tolerability, functional capacity and clinical symptoms.
About MyoKardia
MyoKardia is a clinical stage biopharmaceutical company pioneering a precision medicine approach to discover, develop and commercialize targeted therapies for the treatment of serious and rare cardiovascular diseases. MyoKardia’s initial focus is on the treatment of heritable cardiomyopathies, a group of rare, genetically-driven forms of heart failure that result from biomechanical defects in cardiac muscle contraction. MyoKardia has used its precision medicine platform to generate a pipeline of therapeutic programs for the chronic treatment of the two most prevalent forms of heritable cardiomyopathy—hypertrophic cardiomyopathy, or HCM, and dilated cardiomyopathy, or DCM. MyoKardia’s most advanced product candidate, MYK-461, is an orally-administered small molecule designed to reduce excessive cardiac muscle contractility leading to HCM and has been evaluated in three Phase 1 clinical trials. MyoKardia is now studying MYK-461 in a Phase 2 PIONEER-HCM pilot study in symptomatic oHCM, for which the FDA has granted MYK-461 Orphan Drug Designation. A cornerstone of the MyoKardia platform is the Sarcomeric Human Cardiomyopathy Registry, or SHaRe, a multi-center, international repository of clinical and laboratory data on individuals and families with genetic heart disease, which MyoKardia helped form in 2014. MyoKardia believes that SHaRe, currently consisting of data from approximately 10,000 individuals, is the world’s largest registry of patients with heritable cardiomyopathies. MyoKardia’s mission is to change the world for patients with serious cardiovascular disease through bold and innovative science. For more information, please visit www.myokardia.com.
Investor Contact:
Beth DelGiacco
Stern Investor Relations, Inc.
212-362-1200
beth@sternir.com
Media Contact:
Steven Cooper
Edelman
415-486-3264
steven.cooper@edelman.com
SANTA CLARA, Calif., Nov. 4, 2016 — Hortonworks, Inc.® (NASDAQ: HDP), a leading innovator of open and connected data platforms, today announced that members of its executive management team will present at the following conferences. The presentations will be webcast and available on the Investor Relations page of the Hortonworks website http://investors.hortonworks.com/:
- 2016 RBC Capital Markets Technology, Internet, Media and Telecommunications Conference in New York, NY, November 9, 2016. Presentation by Scott Davidson, Chief Financial Officer, at 9:30 a.m. ET.
- UBS Global Technology Conference in San Francisco, CA, November 15, 2016. Presentation by Scott Davidson, Chief Financial Officer, at 10:15 a.m. PT.
- Credit Suisse 2016 Annual Technology Conference in Scottsdale, AZ, December 1, 2016. Presentation by Rob Bearden, Chief Executive Officer, at 1:30 p.m. MT.
- Barclays Global Technology, Media and Telecommunications Conference in San Francisco, CA, December 7, 2016. Presentation by Scott Davidson, Chief Financial Officer, at 3:30 p.m. PT.
About Hortonworks
Hortonworks is an industry leading innovator that creates, distributes and supports enterprise-ready open data platforms and modern data applications that deliver actionable intelligence from all data: data-in-motion and data-at-rest. Hortonworks is focused on driving innovation in open source communities such as Apache Hadoop, Apache NiFi and Apache Spark. Along with its 1,800+ partners, Hortonworks provides the expertise, training and services that allow customers to unlock transformational value for their organizations across any line of business.
Hortonworks, Powering the Future of Data, HDP and HDF are registered trademarks or trademarks of Hortonworks, Inc. and its subsidiaries in the United States and other jurisdictions. For more information, please visit www.hortonworks.com. All other trademarks are the property of their respective owners.
For Additional Information Contact:
Reuben Gallegos
VP, Corporate Development
rgallegos@hortonworks.com
650-305-7806
ATHENS, GREECE–(Nov 3, 2016) – Globus Maritime Limited (“Globus” or the “Company,”) (NASDAQ: GLBS), a dry bulk shipping company, announced today that it has received a letter from NASDAQ, indicating that the Company has regained compliance with the $1.00 per share minimum closing bid price requirement for continued listing on the NASDAQ Capital Market, pursuant to the NASDAQ marketplace rules. Since May 9th, 2016, Globus was eligible for an additional 180 calendar day period to regain compliance. For at least 10 consecutive business days from October 20, to November 2, 2016, the closing bid price has been greater than $1.00. NASDAQ indicated within its letter that since the Company has regained compliance with Listing Rule 5550(a)(2) (the “Minimum Bid Price Rule”), this matter is now closed.
About Globus Maritime Limited
Globus is an integrated dry bulk shipping company that provides marine transportation services worldwide and presently owns, operates and manages a fleet of five dry bulk vessels that transport iron ore, coal, grain, steel products, cement, alumina and other dry bulk cargoes internationally. Globus’ subsidiaries own and operate five vessels with a total carrying capacity of 300,571 Dwt and a weighted average age of 8.5 years as of September 30, 2016.
Safe Harbor Statement
This communication contains “forward-looking statements” as defined under U.S. federal securities laws. Forward-looking statements provide the Company’s current expectations or forecasts of future events. Forward-looking statements include statements about the Company’s expectations, beliefs, plans, objectives, intentions, assumptions and other statements that are not historical facts or that are not present facts or conditions. Words or phrases such as “anticipate,” “believe,” “continue,” “estimate,” “expect,” “intend,” “may,” “ongoing,” “plan,” “potential,” “predict,” “project,” “will” or similar words or phrases, or the negatives of those words or phrases, may identify forward-looking statements, but the absence of these words does not necessarily mean that a statement is not forward-looking. Forward-looking statements are subject to known and unknown risks and uncertainties and are based on potentially inaccurate assumptions that could cause actual results to differ materially from those expected or implied by the forward-looking statements. The Company’s actual results could differ materially from those anticipated in forward-looking statements for many reasons specifically as described in the Company’s filings with the Securities and Exchange Commission. Accordingly, you should not unduly rely on these forward-looking statements, which speak only as of the date of this communication. Globus undertakes no obligation to publicly revise any forward-looking statement to reflect circumstances or events after the date of this communication or to reflect the occurrence of unanticipated events. You should, however, review the factors and risks Globus describes in the reports it will file from time to time with the Securities and Exchange Commission after the date of this communication.
New Single Port Gigabit and Fast Ethernet PHYs Solve Rapidly Growing Ethernet Connectivity Needs of Diverse Networking Systems
ALISO VIEJO, Calif., Nov. 3, 2016 — Microsemi Corporation (Nasdaq: MSCC), a leading provider of semiconductor solutions differentiated by power, security, reliability and performance, today announced the availability of highly compact single-port SimpliPHY™ Gigabit Ethernet (GbE) and Fast Ethernet (FE) PHYs with supporting open-source Linux drivers. The new PHYs, including VSC8541 and VSC8531 GbE PHYs, and VSC8540 and VSC8530 FE PHYs, provide a flexible input/output interface in a package as small as 6 mm x 6 mm, enabling ubiquitous Ethernet connectivity.
Targeted to address diverse applications such as factory and building automation, video display arrays, 2-D and 3-D printers, and industrial automation endpoints, the new PHYs complement a large portfolio of Microsemi silicon solutions. This includes Ethernet switches, Power-over-Ethernet (PoE) systems and components, as well as timing integrated circuits (ICs) and field programmable gate arrays (FPGAs) to address wired, wireless and secure Ethernet connectivity needs in carrier, industrial and Internet of Things (IoT) networks.
“These new single-port SimpliPHY GbE and FE PHYs further underscore our commitment to bring cost effective, differentiated Ethernet solutions to Microsemi’s key focus markets, including industrial, IoT, enterprise and carrier/telecommunications,” said Uday Mudoi, vice president, marketing, for Microsemi’s Ethernet Networking Technology (ENT) group. “These new devices, combined with open-source licensed Linux Driver Software and comprehensive design collateral, enable quick time to market for our customers and ecosystem partners.”
Market research firm IHS’s 2015 report, “1G/10G/40G/100G Networking Ports—Biannual Worldwide and Regional Market Size and Forecasts,” forecasts Gigabit Ethernet PHYs’ total annual broadband and infrastructure networking Ethernet copper media port shipments to grow more than 35 percent, from 526 million in 2015 to more than 717 million by 2019. An increasing number of Gigabit Ethernet-enabled end points are connecting into this infrastructure as the technology plays a crucial role in driving connectivity across a wide variety of applications.
The new PHYs deliver innovative capabilities to differentiate original equipment manufacturer (OEM) end-products including:
- Lower power consumption, reduced EMC/EMI and extended product design life cycle with low voltage complementary metal oxide semiconductor (LVCMOS) media independent interface (MII) and management data input/output (MDIO) support at 1.5V, 1.8V, 2.5V, and 3.3V
- Ease of printed circuit board (PCB) design, in a 68-pin 8 mm x 8 mm QFN or a 48-pin 6 mm x 6 mm QFN package
- Enhanced IEEE 1588v2 Precision Time Protocol (PTP) accuracy from a system-level solution, a requirement for future 5G designs
Microsemi PHYs also uniquely offer the ability to run VeriPHY™, a comprehensive cable diagnostics, while the link is actively carrying traffic—allowing superior troubleshooting and monitoring capabilities compared to competitive solutions. Additionally, the new PHYs’ configurable drive strength enables systems compliance with electromagnetic interference (EMI)/electromagnetic compatibility (EMC) certifications, such as FCC Class B and CE.
In addition to the notable cost savings for customers, Microsemi’s new single-port SimpliPHY GbE and FE PHYs offer a Fast-Link Failure 2 (FLF2™) indicator, which identifies whether a link might go down in less than 10 microseconds for 1000Base-T (or < 100 microseconds for 100Base-TX), as well as support for forced 1000BASE-T mode support with auto-reconnect in the event the link should come down. In addition, the VSC8541XMV-03 features 1588v2 start-of-frame (SOF) support when used in reduced gigabit media-independent interface (RGMII) in 1000BASE-T mode, enabling enhanced 1588v2 PTP time stamp accuracy when used with an external FPGA or application-specific integrated circuit (ASIC) that performs Digital Dual Mixer Time Difference (DDMTD) along with 1588v2 PTP time-stamping, such as Microsemi’s SmartFusion™2 system-on-chip (SoC) FPGAs, as well as the necessary DPLL devices and 1588v2 servo algorithm. For more information about Microsemi’s IEEE 1588v2, visit http://www.microsemi.com/design-support/ieee-1588-technology.
Other key features include:
- Comprehensive support for either unmanaged or managed modes with 32 device addressability
- Adjustable drive strength on GMII/RGMII/MII/RMII MAC-to-PHY interfaces, with 1.5V ~ 3.3V
- Industrial temperature (I-Temp) offerings for both GbE and FE PHYs; C-Temp for GbE PHYS
- Configurable recovered clock for Synchronous Ethernet (SyncE) (VSC8541 and VSC8540)
- Low single event upset (SEU) failure-in-time (FIT) of < 80 (VSC8541XMV-03)
Product Availability
Microsemi’s new single-port SimpliPHY Cu GbE and FE PHYs are available for purchase orders now. For more information, visit http://www.microsemi.com/products/ethernet-solutions/gigabit-ethernet-phys and http://www.microsemi.com/products/ethernet-solutions/ethernet-phys/fast-ethernet-phys/fast-ethernet-phys or email sales.support@microsemi.com.
About Microsemi’s Industrial and Industrial IoT Solutions Portfolio
Microsemi is a provider of industrial and industrial Internet of Things (IoT) solutions, products and services for applications such as automation, smart energy, communications, transportation and surveillance, including secure, reliable and low power FPGAs, SoC FPGAs, industrial Ethernet switches and PHYs, PoE integrated circuits (ICs) and midspans, 1588 precision timing and synchronization devices, comprehensive drivers and interfaces ICs including sensor interface devices, power discretes such as Silicon Carbide (SiC) MOSFET and power modules and state-of-the-art audio processing solutions. For more information about Microsemi’s complementary product portfolio for industrial applications, visit http://www.microsemi.com/applications/industrial.
About Microsemi
Microsemi Corporation (Nasdaq: MSCC) offers a comprehensive portfolio of semiconductor and system solutions for aerospace & defense, communications, data center and industrial markets. Products include high-performance and radiation-hardened analog mixed-signal integrated circuits, FPGAs, SoCs and ASICs; power management products; timing and synchronization devices and precise time solutions, setting the world’s standard for time; voice processing devices; RF solutions; discrete components; enterprise storage and communication solutions, security technologies and scalable anti-tamper products; Ethernet solutions; Power-over-Ethernet ICs and midspans; as well as custom design capabilities and services. Microsemi is headquartered in Aliso Viejo, California, and has approximately 4,800 employees globally. Learn more at www.microsemi.com.
Microsemi and the Microsemi logo are registered trademarks or service marks of Microsemi Corporation and/or its affiliates. Third-party trademarks and service marks mentioned herein are the property of their respective owners.
“Safe Harbor” Statement under the Private Securities Litigation Reform Act of 1995: Any statements set forth in this news release that are not entirely historical and factual in nature, including statements related to the availability of its new highly compact single-port SimpliPHY™ Gigabit Ethernet (GbE) and Fast Ethernet (FE) PHYs with supporting open-source Linux drivers, and its potential effects on future business, are forward-looking statements. These forward-looking statements are based on our current expectations and are inherently subject to risks and uncertainties that could cause actual results to differ materially from those expressed in the forward-looking statements. The potential risks and uncertainties include, but are not limited to, such factors as rapidly changing technology and product obsolescence, potential cost increases, variations in customer order preferences, weakness or competitive pricing environment of the marketplace, uncertain demand for and acceptance of the company’s products, adverse circumstances in any of our end markets, results of in-process or planned development or marketing and promotional campaigns, difficulties foreseeing future demand, potential non-realization of expected orders or non-realization of backlog, product returns, product liability, and other potential unexpected business and economic conditions or adverse changes in current or expected industry conditions, difficulties and costs of protecting patents and other proprietary rights, inventory obsolescence and difficulties regarding customer qualification of products. In addition to these factors and any other factors mentioned elsewhere in this news release, the reader should refer as well to the factors, uncertainties or risks identified in the company’s most recent Form 10-K and all subsequent Form 10-Q reports filed by Microsemi with the SEC. Additional risk factors may be identified from time to time in Microsemi’s future filings. The forward-looking statements included in this release speak only as of the date hereof, and Microsemi does not undertake any obligation to update these forward-looking statements to reflect subsequent events or circumstances.
Willdan Group, Inc. (NASDAQ: WLDN), a provider of professional technical and consulting services, today announced that the Board of Directors has elected Thomas D. Brisbin as Chairman of the Board. Tom, who has served as Willdan’s President and CEO since 2007, succeeds Win Westfall, who will continue to serve on Willdan’s Board of Directors.
Willdan also announced the following senior management promotions:
- Michael A. Bieber (Mike) has been named President of Willdan Group, Inc.
- Daniel Chow has been named to the newly-created position of Chief Operating Officer of Willdan Group, Inc.
Tom, who previously had the title of President and Chief Executive Officer of Willdan Group, Inc., will continue to serve as Chief Executive Officer of the Company in addition to his new role as Chairman of the Board.
Mike has served as Senior Vice President, Corporate Development of Willdan since joining the Company in December 2014. Daniel has been in senior management positions at Willdan since joining the Company in 2008, most recently serving as President and Chief Executive Officer of our subsidiaries, Willdan Engineering and Willdan Energy Solutions.
“The senior management appointments announced today reflect the Board of Directors’ goal to create a management structure and team that supports the continued growth of Willdan and reflects our succession planning efforts,” said Tom Brisbin. “Since joining Willdan in 2014, Mike has spearheaded the M&A activity that has expanded our energy efficiency services capabilities, and has significantly contributed to our strong growth in revenue, earnings and cash flow. Daniel has done an excellent job leading our Engineering Services segment, which has steadily grown its customer base and generated higher levels of revenue and profits in each of the past three years. We believe we have exceptional opportunities to create additional long-term value for our shareholders, and Mike and Daniel have the skill set, experience and expertise to effectively lead the Company in the years ahead.”
About Thomas D. Brisbin
Thomas D. Brisbin was appointed President and Chief Executive Officer of Willdan Group in April 2007. Tom previously was vice president of and consultant for AECOM Technology Corporation, or AECOM, since spring 2004. At AECOM, a company focused on infrastructure, environment and facilities engineering contracts, Tom was responsible for developing the company’s environmental business. Prior to joining AECOM, Tom was chief operating officer and executive vice president of Tetra Tech, Inc., or Tetra Tech, a leading provider of consulting, engineering and technical services, for five years. Prior to that, he was employed by Planning Research Corporation, or PRC, a systems analysis and management consulting company and wholly-owned subsidiary of The Black & Decker Corporation, from 1978 to 1995 and was co-founder and President of PRC Environmental Management, Inc. During his tenure at PRC, he was involved in all aspects of operations, marketing and finance. Before joining PRC, he was a research associate at Argonne National Laboratory. He has also served as an adjunct professor at the Illinois Institute of Technology. Tom holds a B.S. degree from Northern Illinois University and a Ph.D. in Environmental Engineering from Illinois Institute of Technology. He also completed Harvard Business School’s Advanced Management Program in 1988.
About Michael A. Bieber
Michael A. Bieber was appointed Senior Vice President, Corporate Development of Willdan Group, Inc. in December 2014. Previously, he served as Senior Vice President at Tetra Tech, where he served in a number of leadership roles for over 18 years. From March 2007 to December 2014, Mike managed Tetra Tech’s mergers and acquisitions and investor relations functions, overseeing over fifty acquisitions. From 2005 to 2007, Mike managed Tetra Tech’s corporate business development group, where he was responsible for overseeing internal business development, marketing and communications. From January 2000 to December 2014, Mike also worked in Tetra Tech’s investor relations group. From 1996 to 2000, he was a proposal manager in Tetra Tech’s corporate marketing group. From 1994 to 1996, he served at CRC, Inc., and its successor, as a strategic business development consultant to large defense, infrastructure, and environmental firms. Prior to 1994, Mike worked for IT Corporation (now CB&I) where he served as project manager and engineer on government nuclear and commercial environmental projects. Mike holds a B.S. degree in Civil Engineering from the Tennessee Technological University.
About Daniel Chow
Daniel Chow has served as President and Chief Executive Officer of our subsidiaries Willdan Engineering and Willdan Energy Solutions since August 2016. Daniel joined Willdan in December 2008 as President and Chief Executive Officer of Willdan Engineering. Prior to joining Willdan, Daniel was the Vice President of AMEC Earth & Environmental, Inc., a subsidiary of AMEC plc, a global provider of high value consultancy, engineering and project management services to the energy, power and process industries, from April 2004 to December 2008. Prior to AMEC, Daniel worked at Tetra Tech EM Inc. (formerly PRC Environmental Management, Inc.) for over 20 years and held various senior management positions, including Vice President of US operations. During Daniel’s tenure with these firms, he was responsible for establishing new offices and developing and implementing management systems firmwide to enhance operations. He also led the pursuit and management of multi-million dollar contracts for government clients that included the U.S. Navy and the U.S. Army Corps of Engineers. Daniel received his B.Sc. in Mechanical Engineering from Tennessee Technological University and his Master’s Degree in Environmental Engineering from Illinois Institute of Technology. He is a registered professional engineer in the state of Illinois and Guam.
About Willdan
Willdan provides professional consulting and technical services to utilities, public agencies and private industry throughout the United States. Willdan’s service offerings span a broad set of complementary disciplines that include energy efficiency and sustainability, engineering and planning, financial and economic consulting, and national preparedness. Willdan provides integrated technical solutions to extend the reach and resources of its clients, and provides all services through its subsidiaries specialized in each segment. For additional information, visit Willdan’s website at www.willdan.com.
Forward-Looking Statements
Statements in this press release that are not purely historical, including statements regarding Willdan’s intentions, hopes, beliefs, expectations, representations, projections, estimates, plans or predictions of the future are forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. The forward-looking statements involve risks and uncertainties including, but not limited to, the risk that Willdan will not be able to continue the growth it has experienced in recent years. It is important to note that Willdan’s actual results could differ materially from those in any such forward-looking statements. Factors that could cause actual results to differ materially include, but are not limited to, a slowdown in the local and regional economies of the states where Willdan conducts business and the loss of or inability to hire additional qualified professionals. Willdan’s business could be affected by a number of other factors, including the risk factors listed from time to time in Willdan’s SEC reports including, but not limited to, the Annual Report on Form 10-K filed for the year ended January 1, 2016. Willdan cautions investors not to place undue reliance on the forward-looking statements contained in this press release. Willdan disclaims any obligation to, and does not undertake to, update or revise any forward-looking statements in this press release.
Itron, Inc. (NASDAQ: ITRI) announced today that Philip Mezey, Itron’s president and chief executive officer, will present at Baird’s 46th Annual Global Industrial Conference at the Four Seasons Hotel in Chicago. The company’s investor presentation will be webcast live on Wednesday, Nov. 9, 2016 at 5:30 p.m. EST / 2:30 p.m. PST.
The live audio webcast and investor presentation will be accessible via Itron’s Investor Relations website at http://investors.itron.com/events.cfm. A replay of the webcast will be available for 30 days following the event.
About Itron
Itron is a world-leading technology and services company dedicated to the resourceful use of energy and water. We provide comprehensive solutions that measure, manage and analyze energy and water. Our broad product portfolio includes electricity, gas, water and thermal energy measurement devices and control technology; communications systems; software; as well as managed and consulting services. With thousands of employees supporting nearly 8,000 customers in more than 100 countries, Itron applies knowledge and technology to better manage energy and water resources. Together, we can create a more resourceful world. Join us: www.itron.com.
Itron® is a registered trademark of Itron, Inc. All third-party trademarks are property of their respective owners and any usage herein does not suggest or imply any relationship between Itron and the third party unless expressly stated.
Itron, Inc.
Barbara Doyle, 509-891-3443
Vice President, Investor Relations
Findings Reveal Higher Earnings for Those Defining New Care Models in Response to Health Care Reform
ST. LOUIS, Nov. 3, 2016 — Cejka Executive SearchSM ― in partnership with the American Association for Physician Leadership® ― today announced the results of the 10th biennial Physician Leadership Compensation Survey. According to the survey, total median compensation for physicians in leadership in 2016 is $350,000, a three-year gain of 8% since the last survey in 2013. While fairly consistent with growth over the past seven years, this lags pre-recession two-year growth rates of 12% reported in 2007.
“Given health care reform and the continued attention on costs, including executive compensation, we don’t expect physician leader compensation to return to pre-recession growth rates anytime soon,” said Paul Esselman, Cejka Executive Search’s Senior EVP and Managing Director. “However, there are emerging roles in response to the shift toward value-based care that provide physician leaders with significantly greater opportunities for earnings, as well as strategic input and organizational influence.”
Chief Executive Officer Not Always the Highest Paying Job
The highest-paid physician executives on average earned $499,000 and served in emerging roles that include: Physician in Chief, Chief Strategy Officer, Chief Transformational Officer, Chief Innovation Officer and Chief Integration Officer.
“Physicians in these transformative roles are often tasked with ‘connecting the dots’ across the organization and care continuum to achieve the greater efficiency and effectiveness of care required by newer reimbursement models, including population health management and accountable care,” said Joyce Tucker, Cejka Executive Search EVP and Managing Principal.
Trending Compensation for C-Suite Physician Leaders
(Median compensation 2016 vs. 2013)
Emerging Roles, C-Suite: $499,000 vs. $469,000, up 6%
Chief Executive Officer/President: $437,500 vs. $410,000, up 7%
Chief Medical Officer: $388,000 vs. $365,000, up 6%
Chief Quality/Patient Safety Officer: $375,000 vs. $375,000
Chief Information Officer/Chief Medical Information Officer: $372,500 vs. $315,000, up 18%
The Growing Role of “Big Data” Drives Compensation Higher
The greatest increase in C-suite compensation since 2013 was 18% for physicians in the Chief Information Officer (CIO) or Chief Medical Information Officer (CMIO) roles. The spike can be explained by the roles’ shift in focus ― from electronic medical records implementation to ensuring the usability of data to support preventative care at the individual provider level and risk-based accountable care at the enterprise-level. “Clearly, there is perceived value in having a physician leader drive these initiatives and facilities are willing to compensate accordingly,” said Esselman.
Other Pathways to Higher Compensation
Those who operate at a system-wide level, hold post-graduate degrees or certifications or whose compensation is most aligned with organizational goals, also earned more. For example, physician leaders working at the corporate or parent-level of a health system saw an average 67% spike in median compensation since 2013. As compared to physician leaders with no post-graduate degrees, a master’s in business administration (MBA) earned respondents on average 13% more and a certified physician executive (CPE) on average earned 4% more. In addition, leaders who allocated more time to administration and whose performance-based pay was a higher percentage of total compensation earned more as well.
Demand for Clinical Quality Leadership Remains Strong
Outside of the C-suite, the highest three-year pay gain was 26% for physician leaders focused on clinical initiatives serving as president of the medical staff or medical director, assistant or associate. The number of respondents in these positions also rose as a percent of total physician leaders, from 5% in 2013 to 8% in 2016. This indicates an emphasis on building the next organizational level of quality leaders in response to quality outcome measures now increasingly tied to reimbursements.
More Complex Physician Leader Roles Call for Expanded Skills
Physician leaders are serving in more strategic and complex roles than in the past. For example, 61% say they have more strategic input than the previous year, and more than half (54%) have multiple or shared administrative reporting relationships. Of those, 49% (versus 24% in 2013) are administratively accountable to more than one person, and 29% (versus 19% in 2013) have shared direct reports.
“Education areas selected by physician leaders as those having the greatest ability to enhance their job performance, demonstrate the strategic nature of physician leader responsibilities,” said Dr. Peter Angood, American Association for Physician Leadership® CEO and President.
These include: financial analysis, change management, strategic planning, population health management, physician engagement and conflict resolution.
About the Survey
The 2016 Physician Leadership Compensation Survey was conducted by Cejka Executive Search in partnership with the American Association for Physician Leadership®. It contains self-reported compensation data collected from 2,353 physician leaders in July 2016 based on 2015 total compensation. This includes salary, bonuses, incentive payments, research stipends, honoraria and distribution of profits. The data also includes the total compensation received for both administrative duties and the clinical practice of medicine. For more research results or to purchase a copy of the full 2016 Physician Leadership Compensation Survey visit www.cejkaexecutivesearch.com/2016-physician-leadership-compensation-survey
About Cejka Executive Search
Cejka Executive Search ranks among the top five largest health care executive search firms in the United States, providing services exclusively to the healthcare industry for more than 35 years. The firm partners with health care organizations to identify and recruit talented C-level executives, physician leaders, key members of senior management and academic medicine faculty. Cejka Executive Search is a Cross Country Healthcare Inc.® (Nasdaq: CCRN) company, a diversified leader in health care staffing services.
About the American Association for Physician Leadership®
The American Association for Physician Leadership® is the preeminent U.S.-based organization for physician leaders worldwide. Since its founding in 1975, the association, formerly known as the American College of Physician Executives (ACPE), has grown to serve physicians at all stages of their careers through leadership education, career support and policy advocacy. The organization has an active membership — including chief executive officers, chief medical officers, vice presidents of medical affairs and other leadership physicians in 47 countries. The expanding portfolio of the association includes more than 100 courses, numerous certificate programs, five master’s degree programs and a specialized career support program customized for physicians.
Media Contact:
Lisa McCarthy
on behalf of Cejka Executive Search lisamc@digitalinfusion.net, (954) 328-1745
BOSTON, Nov. 03, 2016 — EnerNOC, Inc. (Nasdaq:ENOC), a leading provider of energy intelligence software (EIS) and demand response solutions, announced today that its demand response portfolio in Korea surpassed one gigawatt—roughly equivalent to the amount of power generated by a nuclear power plant.
EnerNOC entered the market in late 2014, following legislation earlier that year that introduced demand response into the country’s wholesale capacity market. Since establishing operations in Korea, EnerNOC has become the preferred demand response provider to some of the region’s largest enterprises, public institutions, and universities, including S-Oil, COEX, Korea University, and Seoul City Government.
“We partnered with EnerNOC because they’re the world’s leader in demand response. They have the experience we rely on to ensure that we can participate in demand response without compromising our operations,” said JaeHee Kang, Facility Manager at Korea University.
Demand response has grown rapidly in Korea, propelled by the government’s strong commitment to creating a sustainable and competitive market and EnerNOC’s ability to leverage its industry-leading technology and experience to scale quickly.
“Korea relies on fuel imports to meet nearly 100% of its electricity needs. Demand response gives the Korean government increased flexibility to meet demand in a clean, cost-efficient way, with a reliable domestic energy resource, while at the same time allowing Korean businesses to use their flexibility to earn valuable new revenue streams,” said David Brewster, President, EnerNOC.
“Our success in Korea has been instrumental in stimulating interest throughout Asia. We’re excited about the emerging opportunities we see on the horizon to make DR a more integral part of the resource mix throughout the region,” added Brewster.
About EnerNOC
EnerNOC is a leading provider of energy intelligence software (EIS) and demand response solutions. With capabilities to better address budgets and procurement, utility bill management, facility analysis and optimization, sustainability and reporting, project tracking, and demand management, EnerNOC’s SaaS platform helps enterprises control energy costs, mitigate risk, and streamline compliance and sustainability reporting. EnerNOC also offers access to more demand response programs worldwide than any other provider, offering enterprises a valuable payment stream to further enhance bottom line results and utilities and grid operators a reliable, cost-effective demand-side resource. For more information, visit www.enernoc.com.
Safe Harbor Statement
Statements in this press release regarding management’s future expectations, beliefs, intentions, goals, strategies, plans or prospects, including, without limitation, statements relating to the Company’s future financial performance on both a GAAP and non-GAAP basis, and the future growth and success of the Company’s energy intelligence software and demand response solutions, may constitute forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 and other federal securities laws. Forward-looking statements can be identified by terminology such as “anticipate,” “believe,” “could,” “could increase the likelihood,” “estimate,” “expect,” “intend,” “is planned,” “may,” “should,” “will,” “will enable,” “would be expected,” “look forward,” “may provide,” “would” or similar terms, variations of such terms or the negative of those terms. Such forward-looking statements involve known and unknown risks, uncertainties and other factors including those risks, uncertainties and factors referred to under the section “Risk Factors” in EnerNOC’s most recent Annual Report on Form 10-K and subsequent Quarterly Reports on Form 10-Q, as well as other documents that may be filed by EnerNOC from time to time with the Securities and Exchange Commission. As a result of such risks, uncertainties and factors, the Company’s actual results may differ materially from any future results, performance or achievements discussed in or implied by the forward-looking statements contained herein. EnerNOC is providing the information in this press release as of this date and assumes no obligations to update the information included in this press release or revise any forward-looking statements, whether as a result of new information, future events or otherwise.

EnerNOC Media Relations:
Sarah McAuley
617.532.8195
news@enernoc.com
EnerNOC Investor Relations:
Christopher Sands
617.692.2569
ir@enernoc.com
SHANGHAI, Nov. 2, 2016 — SPI Energy Co., Ltd. (“SPI Energy” or the “Company”) (Nasdaq: SPI), a global provider of photovoltaic (PV) solutions for business, residential, government and utility customers and investors, today announced changes to the senior management team and board of directors of the Company (the “Board”), effective on October 29, 2016:
Mr. Roger Dejun Ye has resigned as Executive Vice President in charge of the Company’s solar business but will remain as a non-executive director of the Board;
Mr. Minghua Zhao, who currently serves as Joint Chief Operating Officer (“COO”) of the Company’s China domestic business, has been appointed as a director to the Board; and
Mr. Fei Yun, who previously served as General Manager of Xinghang PV Technology (Suzhou) Co., Ltd., has joined the Company as Senior Vice President in charge of R&D and Solar Technology Development.
“I would like to thank Roger for his contributions to the development of Company’s solar business during his tenure and we look forward to continuing to work closely with Roger in his role as a director of the Board. On behalf of the management team and the Board, I also would like to extend our warm welcome to Minghua in joining the Board and Fei in joining the Company,” said Xiaofeng Peng, Chairman and Chief Executive Officer of SPI Energy.
Mr. Minghua Zhao currently serves as Joint COO of the Company’s China domestic business and previously served as Senior Vice President of the Company’s finance service business between February 2015 and June 2016. Before he joined the Company in February 2015, Mr. Zhao served as general manager of Suzhou Industrial Park Chengcheng Enterprises Guarantee Co., Ltd., a financial services company, and from 2003 to 2009 as president of Suzhou Industrial Park Branch of Suzhou Bank. Prior to that, he worked at CITIC Bank for six years. Mr. Zhao graduated from Jiangsu Province Business School in 1997 with a degree in Business Administration and from Southwestern University of Finance and Economics in 2008 with a degree in Business Management.
Mr. Fei Yun has more than 30 years of experience in the research and development of solar cells, PV systems and senior management role in the industry in Australia and China. Mr. Fei Yun joined us from Xinghang PV Technology (Suzhou) Co., Ltd. where he has served as General Manager since July 2014. Previously, Mr. Yun held senior management positions at various solar companies, including as Vice President of Technology at LDK Solar Co., Ltd. from February 2010 to June 2013; Chief Technology Officer at Solar Enertech Corp. from December 2007 to January 2010; Vice President of Technology at SolarFun (Now Hanwha Solar One) from July 2006 to November 2007; General Manager and Chief Engineer at Tera Solar Technologies from March 2004 to June 2006. Mr. Yun received his bachelor’s degree in Physics from Jinan University, his master’s degree in Solar Energy from the Asian Institute of Technology(AIT) in Bangkok, Thailand. He also had nearly 10 years of research and development experience in silicon-based solar cells at the ARC Photovoltaics Centre of Excellence at the University of New South Wales in Sydney, Australia, his expertise is focused on the high efficiency silicon solar cell.
About SPI Energy Co., Ltd.
SPI Energy Co., Ltd. is a global provider of photovoltaic (PV) solutions for business, residential, government and utility customers and investors. SPI Energy focuses on the downstream PV market including the development, financing, installation, operation and sale of utility-scale and residential solar power projects in China, Japan, Europe and North America. The Company operates an innovative online energy e-commerce and investment platform, www.solarbao.com, which enables individual and institutional investors to purchase innovative PV-based investment and other products; as well as www.solartao.com, a B2B e-commerce platform offering a range of PV products for both upstream and downstream suppliers and customers. The Company has its operating headquarters in Shanghai and maintains global operations in Asia, Europe, North America and Australia.
Safe Harbor Statement
This release contains certain “forward-looking statements.” These statements are forward-looking in nature and subject to risks and uncertainties that may cause actual results to differ materially. All forward-looking statements included in this release are based upon information available to the Company as of the date of this release, which may change, and the Company undertakes no obligation to update or revise any forward-looking statements, except as may be required under applicable securities law.
For investors and media inquiries please contact:
Investor Relations Department
SPI Energy Co., Ltd.
pearl.peng@spisolar.com
+86 21 8012 9135
Tony Tian, CFA
Weitian Group LLC
tony.tian@weitian-ir.com
+1 732 910 9692
RTG4 Space Flight Devices are Now Available in Various Screening Flows
ALISO VIEJO, Calif., Nov. 2, 2016 — Microsemi Corporation (Nasdaq: MSCC), a leading provider of semiconductor solutions differentiated by power, security, reliability and performance, today announced its RTG4™ high-speed signal processing radiation-tolerant field programmable gate arrays (FPGAs) have achieved MIL-STD-883 Class B qualification, meeting the industry’s standard for qualifying microelectronic devices suitable for use within aerospace and defense electronic systems. Microsemi also announced the availability of RTG4 space flight models in various screening flows including the B Flow and the Extended Flow (E Flow), providing additional screening options and a higher level of reliability assurance required in many critical space applications.
“Achieving this important qualification strengthens Microsemi’s leadership position in space and reinforces our commitment to providing the highest quality and reliability solutions to meet the increasing demands of modern satellite payloads,” said Minh Nguyen, Microsemi’s senior marketing manager, space and aviation. “Customers can now procure RTG4 FPGAs screened to B Flow per MIL-STD-883 Class B and Microsemi’s E Flow, making it easy for customers to select RTG4 for programs requiring the highest performing FPGAs.”
Microsemi is a Qualified Manufacturers List (QML)-certified manufacturer of high reliability FPGAs for space applications. Meeting the stringent standards of the MIL-STD-883 Class B qualification paves the way for Microsemi’s RTG4 FPGAs to secure QML Class Q and QML Class V qualifications in the near future. Adding Microsemi’s E Flow to these devices offers additional testing for space applications requiring a screening level beyond the MIL-STD-883 Class B standard.
To achieve the new qualification, Microsemi’s RTG4 FPGAs passed a series of environmental tests to determine resistance to deleterious effects of natural elements and conditions surrounding defense and space operations, as well as mechanical and electrical tests. RTG4 units from multiple wafer lots successfully completed 1,000-hour high temperature life tests, proving the high reliability of RTG4 flash cells in extreme conditions.
RTG4 FPGAs bring new capabilities to the market and help solve satellite signal processing congestion, while having high reliability as shown in the recent MIL-STD-883 Class B qualification. According to Euroconsult’s 2015 report titled, “Satellites to Be Built and Launched by 2024,” 60 percent more satellites will be launched by 2024 versus the past decade. This increase is driven primarily by civilian government agencies as established space countries replace and expand their in-orbit satellite systems and more countries acquire their first operational satellite systems.
About Microsemi’s RTG4 FPGAs and Development Kit
RTG4 FPGAs bring new capabilities to the market and combine a wealth of features with the highest quality and reliability to meet the increasing demands of modern satellite payloads. The devices feature reprogrammable flash configuration, making prototyping easier for customers. RTG4’s reprogrammable flash technology offers complete immunity to radiation-induced configuration upsets in the harshest radiation environments, without the configuration scrubbing required with SRAM FPGA technology. RTG4 supports space applications requiring up to 150,000 logic elements, and each includes a LUT4 and a flip-flop with built-in triple module redundancy (TMR). The devices also features total ionizing dose (TID) beyond 100 kilorads, as well as high system performance of up to 300 MHz without single event transient (SET) mitigation.
The RTG4 Development Kit features Microsemi’s Libero SoC Design Suite, offering high productivity with its comprehensive, easy to learn, easy to adopt development tools for designing with Microsemi’s radiation-tolerant FPGAs. The suite integrates industry standard Synopsys SynplifyPro synthesis and Mentor Graphics ModelSim simulation with best-in-class constraints management, debug capabilities and secure production programming support.
RTG4 is Microsemi’s latest development in a long history of radiation-tolerant FPGAs that are found in many NASA and international space programs. For more information, visit http://www.microsemi.com/products/fpga-soc/radtolerant-fpgas/rtg4.
Microsemi Leading Space Innovation for More than Half a Century
With one of the industry’s most comprehensive portfolios of space products, Microsemi provides radiation-tolerant (FPGAs, radiation-hardened mixed-signal integrated circuits (ICs), radiation-hardened DC-to-DC converters, precision time and frequency solutions, linear and POL hybrids, custom hybrid solutions, and radiation-hardened discretes including the broadest portfolio of JANS Class diodes and bipolar products. Microsemi is committed to supporting its products throughout the lifetime of its customer programs. The company continues to innovate and expand its portfolio, with recent additions including its LX7730 radiation-tolerant telemetry controller IC providing key functions for sensor monitoring, attitude and payload control, as well as its RTG4™ high-speed signal processing radiation-tolerant FPGA family. The RTG4’s reprogrammable flash technology offers complete immunity to radiation-induced configuration upsets in the harshest radiation environments, requiring no configuration scrubbing, unlike SRAM FPGA technology. For more information about Microsemi’s space products, visit http://www.microsemi.com/applications/space.
About Microsemi
Microsemi Corporation (Nasdaq: MSCC) offers a comprehensive portfolio of semiconductor and system solutions for aerospace & defense, communications, data center and industrial markets. Products include high-performance and radiation-hardened analog mixed-signal integrated circuits, FPGAs, SoCs and ASICs; power management products; timing and synchronization devices and precise time solutions, setting the world’s standard for time; voice processing devices; RF solutions; discrete components; enterprise storage and communication solutions, security technologies and scalable anti-tamper products; Ethernet solutions; Power-over-Ethernet ICs and midspans; as well as custom design capabilities and services. Microsemi is headquartered in Aliso Viejo, California, and has approximately 4,800 employees globally. Learn more at www.microsemi.com.
Microsemi and the Microsemi logo are registered trademarks or service marks of Microsemi Corporation and/or its affiliates. Third-party trademarks and service marks mentioned herein are the property of their respective owners.
“Safe Harbor” Statement under the Private Securities Litigation Reform Act of 1995: Any statements set forth in this news release that are not entirely historical and factual in nature, including without limitation statements related to its RTG4™ high-speed signal processing radiation-tolerant field programmable gate arrays (FPGAs) achieving MIL-STD-883 Class B qualification, meeting the industry’s standard for qualifying microelectronic devices suitable for use within aerospace and defense electronic systems, and its potential effects on future business, are forward-looking statements. These forward-looking statements are based on our current expectations and are inherently subject to risks and uncertainties that could cause actual results to differ materially from those expressed in the forward-looking statements. The potential risks and uncertainties include, but are not limited to, such factors as rapidly changing technology and product obsolescence, potential cost increases, variations in customer order preferences, weakness or competitive pricing environment of the marketplace, uncertain demand for and acceptance of the company’s products, adverse circumstances in any of our end markets, results of in-process or planned development or marketing and promotional campaigns, difficulties foreseeing future demand, potential non-realization of expected orders or non-realization of backlog, product returns, product liability, and other potential unexpected business and economic conditions or adverse changes in current or expected industry conditions, difficulties and costs in implementing the company’s acquisitions and divestitures strategy or integrating acquired companies, uncertainty as to the future profitability of acquired businesses and realization of accretion from acquisition transactions, difficulties and costs of protecting patents and other proprietary rights, inventory obsolescence and difficulties regarding customer qualification of products. In addition to these factors and any other factors mentioned elsewhere in this news release, the reader should refer as well to the factors, uncertainties or risks identified in the company’s most recent Form 10-K and all subsequent Form 10-Q reports filed by Microsemi with the SEC. Additional risk factors may be identified from time to time in Microsemi’s future filings. The forward-looking statements included in this release speak only as of the date hereof, and Microsemi does not undertake any obligation to update these forward-looking statements to reflect subsequent events or circumstances.
eBay Inc. (NASDAQ:EBAY), a global commerce leader, announced today that it received notice of an unsolicited “mini-tender” offer by TRC Capital Corporation (TRC) to purchase up to 4,000,000 shares of eBay’s common stock at a price of $27.35 per share in cash. The offering price is 4.37% below the closing price per share of eBay’s common stock on October 28, 2016, the last trading day before the offer was commenced. The offer is for approximately 0.36% of the outstanding shares of eBay’s common stock.
eBay does not endorse TRC Capital’s unsolicited mini-tender offer and recommends that shareholders not tender their shares. eBay is not associated with TRC Capital, its mini-tender offer or the mini-tender offer documentation.
Mini-tender offers are not subject to many of the investor protections afforded to larger tender offers, including the filing of disclosure and other tender offer documents with the Securities and Exchange Commission (SEC) and other procedures mandated by U.S. securities laws.
The SEC has cautioned investors that some bidders making mini-tender offers at below-market prices are, “hoping that they will catch investors off guard if the investors do not compare the offer price to the current market price.” The SEC’s guidance to investors on mini-tender offers is available at http://www.sec.gov/investor/pubs/minitend.htm. TRC Capital has made many similar unsolicited mini-tender offers for shares of other public companies.
Shareholders should obtain current market quotations for their shares, consult with their broker or financial advisor, and exercise caution with respect to TRC Capital’s mini-tender offer. eBay recommends that shareholders who have not responded to TRC Capital’s offer take no action. Shareholders who have already tendered their shares may withdraw them at any time prior to 12:01 a.m., New York City time, on November 30, 2016, in accordance with TRC’s offering documents.
eBay encourages brokers and dealers, as well as other market participants, to review the SEC’s letter regarding broker-dealer mini-tender offer dissemination and disclosure at http://www.sec.gov/divisions/marketreg/minitenders/sia072401.htm.
eBay requests that a copy of this press release be included with all distributions of materials relating to TRC Capital’s mini-tender offer related to eBay shares of common stock.
About eBay
eBay Inc. (NASDAQ: EBAY) is a global commerce leader including the Marketplace, StubHub and Classifieds platforms. Collectively, we connect millions of buyers and sellers around the world, empowering people and creating opportunity through Connected Commerce. Founded in 1995 in San Jose, Calif., eBay is one of the world’s largest and most vibrant marketplaces for discovering great value and unique selection. In 2015, eBay enabled $82 billion of gross merchandise volume. For more information about the company and its global portfolio of online brands, visit www.ebayinc.com.
eBay Inc.
Investor Relations Contact:
Selim Freiha
ir@ebay.com
or
Media Relations Contact:
Abby Smith
press@ebay.com
or
Company News:
https://www.ebayinc.com/stories/news/
or
Investor Relations website:
https://investors.ebayinc.com
MINNEAPOLIS, Nov. 02, 2016 — Skyline Medical Inc. (NASDAQ:SKLN) (“Skyline” or “the Company”), producer of the FDA-approved STREAMWAY® System for automated, direct-to-drain medical fluid disposal, announces that it has agreed to grant GLG Pharma, LLC (“GLG”) exclusive rights to market and distribute the STREAMWAY® System in Poland and certain other countries in Central Europe. This builds upon a previously announced arrangement granting GLG exclusive rights to market and distribute STREAMWAY in the U.K. and an initial agreement to develop rapid diagnostic tests that utilize fluid and tissue collected by the STREAMWAY System during procedures.
GLG will be responsible for all sales and marketing activities, including hiring and training the appropriate number of direct sales representatives to cover the 3,800 operating rooms in Poland. Marketing is expected to begin immediately upon receipt of the CE Mark and will be managed from GLG’s facility in Gdansk, Poland.
The agreement will also include the Czech Republic, Latvia, Estonia and Lithuania, with sales activities expected to begin in those countries soon after the introduction in Poland. Skyline applied for CE Mark approval to market STREAMWAY in the European Union and certain other countries in July 2016, following receipt of ISO 13485:2003 certification.
“We are excited to further solidify and expand our relationship with Skyline Medical with this expansion of our exclusive sales and marketing territory, the second agreement we have we have announced this week,” said Richard Gabriel, Co-founder and Chief Operating Officer of GLG Pharma. “Central Europe is expected to be a very attractive market for STREAMWAY System sales, orchestrated by our general manager in Poland. We currently have pharmaceutical and diagnostic development laboratories in Poland, which are supported by grants from the Polish government. The STREAMWAY System will make an excellent addition to our portfolio of products in development.”
In June 2016 STREAMWAY received ISO 13485:2003 certification, an internationally recognized quality standard for medical devices that is awarded when an organization demonstrates its ability to provide medical devices and related services that consistently meet customer and regulatory requirements applicable to medical devices and related services, and is a requirement for medical device clearance in Canada, the EU and a majority of other countries that require products meet EU safety, health and environmental requirements.
Under the terms of an agreement announced in September 2016, GLG intends to develop rapid diagnostic tests that utilize fluid and tissue collected by the STREAMWAY System during procedures. Initial tests are anticipated to include cancer biomarkers and infectious diseases. The oncology test panels will feature GLG’s patented inhibitors of Signal Transducers and Activators of Transcription 3 (STAT3), which are in preclinical development for a new generation of targeted therapies.
About GLG, LLC.
Founded in 2009 and located in Jupiter, Fla., GLG Pharma, LLC is a privately held, early stage, biotechnology company developing personalized therapies for patients with cancer and other proliferative diseases. GLG Pharma’s therapeutics are expected to aid in the treatment of a wide variety of cancers and address unmet needs in the multi-billion dollar anti-cancer market with potentially greater efficacy and fewer side effects than existing therapies. For more information on GLG Pharma visit: http://www.glgpharma.com.
About the STREAMWAY System
Skyline Medical’s revolutionary, FDA-cleared STREAMWAY System is the first true direct-to-drain fluid disposal system designed specifically for medical applications, such as radiology, endoscopy, urology and cystoscopy procedures. It connects directly to a facility’s plumbing system to automate the collection, measurement and disposal of waste fluids, and minimizes human intervention for better safety while improving compliance with Occupational Safety and Health Administration (OSHA) and other regulatory agency safety guidelines. It also provides unlimited capacity for increased efficiency in the operating room, which leads to greater profitability. The STREAMWAY eliminates canisters to reduce overhead costs and provides greater environmental stewardship by helping to eliminate the approximately 50 million potentially disease-infected canisters that go into landfills annually in the U.S.
About Skyline Medical Inc.
Skyline Medical Inc. produces a fully automated, patented, FDA-cleared, waste fluid disposal system that virtually eliminates staff exposure to blood, irrigation fluid and other potentially infectious fluids found in the healthcare environment. Antiquated manual fluid handling methods — which require hand carrying and emptying filled fluid canisters — present an exposure risk and potential liability. Skyline Medical’s STREAMWAY System fully automates the collection, measurement and disposal of waste fluids and is designed to: 1) reduce overhead costs to hospitals and surgical centers, 2) improve compliance with OSHA and other regulatory agency safety guidelines, 3) improve efficiency in the operating room, and radiology and endoscopy departments — leading to greater profitability, and 4) provide greater environmental stewardship by helping to eliminate the approximately 50 million potentially disease-infected canisters that go into landfills annually in the United States. For additional information, please visit www.skylinemedical.com.
Forward-looking Statements:
Certain of the matters discussed in this announcement contain forward-looking statements that involve material risks to and uncertainties in the Company’s business that may cause actual results to differ materially from those anticipated by the statements made herein. Such risks and uncertainties include, among other things, current negative operating cash flows and a need for additional funding to finance our operating plan; the terms of any further financing, which may be highly dilutive and may include onerous terms; unexpected costs and operating deficits, and lower than expected sales and revenues; uncertain willingness and ability of customers to adopt new technologies and other factors that may affect further market acceptance, if our product is not accepted by our potential customers, it is unlikely that we will ever become profitable, adverse economic conditions; the potential delisting of the Company’s common stock on The Nasdaq Capital Market as a result of the Company’s failures to comply with listing standards, in which case the liquidity of our common stock would likely be impaired and there would likely be a reduction in our coverage by security analysts and the news media, thereby resulting in lower prices for our common stock than might otherwise prevail; adverse results of any legal proceedings; the volatility of our operating results and financial condition; inability to attract or retain qualified senior management personnel, including sales and marketing personnel; our ability to establish and maintain the proprietary nature of our technology through the patent process, as well as our ability to possibly license from others patents and patent applications necessary to develop products; the Company’s ability to implement its long range business plan for various applications of its technology, including the possibility that the development of applicable technologies by GLG Pharma, LLC will be delayed, will not occur or will not receive applicable regulatory approvals on a timely basis; the Company’s ability to consummate its joint venture with Electronic On-Ramp, Inc.; the Company’s ability to enter into agreements with any necessary marketing and/or distribution partners; the impact of competition, the obtaining and maintenance of any necessary regulatory clearances applicable to applications of the Company’s technology; and management of growth and other risks and uncertainties that may be detailed from time to time in the Company’s reports filed with the Securities and Exchange Commission, which are available for review at www.sec.gov. This is not a solicitation to buy or sell securities and does not purport to be an analysis of the Company’s financial position. See the Company’s most recent Annual Report on Form 10-K, and subsequent reports and other filings at www.sec.gov.

Contact:
Investors
LHA
Kim Sutton Golodetz
(212) 838-3777
kgolodetz@lhai.com
MoneyInfo, LLC
Charles Moskowitz
(781) 826-8882
cam@moneyinfo-llc.com
GTCR to pay $23.00 per share, representing a 37% premium to Inteliquent’s closing stock price on November 1, 2016
Transaction valued at approximately $800 million
CHICAGO, Nov. 02, 2016 — Inteliquent, Inc. (NASDAQ:IQNT), a premier interconnection partner for communications service providers of all types, announced today that it has entered into a definitive agreement to be acquired by an affiliate of GTCR LLC, a leading private equity firm, and merged with a subsidiary of Onvoy, LLC a fast-growing leader in Communications Enablement services. Under the terms of the agreement, Inteliquent stockholders of record will receive $23.00 in cash per share of common stock, which represents a 37% premium to Inteliquent’s closing stock price on November 1, 2016. The value of the transaction is approximately $800 million.
“Over the past several quarters, Inteliquent has been transforming its business to become a leader in the next-generation communications services market,” said Matt Carter, Inteliquent’s Chief Executive Officer. “The acquisition of Inteliquent by GTCR and Onvoy validates our Growth Forward strategy. We believe this transaction will deliver immediate, significant and certain cash value to our stockholders while creating a market leading provider.”
“We are excited to partner with the Inteliquent and Onvoy management teams to create a leading provider of communications enablement solutions,” added GTCR Managing Director Lawrence Fey. “The combination of Inteliquent and Onvoy is transformational and creates an entity that is well positioned to provide robust next-generation solutions to the communications enablement market.”
“Inteliquent’s commitment to the core switching infrastructure has earned the trust of the nation’s top carriers. We believe this will lead to additional opportunities for other carriers to partner with Inteliquent to outsource network infrastructure and achieve cost savings without sacrificing quality and reliability,” said Fritz Hendricks, Chief Executive Officer of Onvoy. “We look forward to working with the Inteliquent team to continue the network expansion and to empower innovation for our shared customer base.”
The combined company intends to continue to maintain a significant presence in Chicago.
Additional Transaction Details
The Inteliquent Board of Directors unanimously approved the transaction and agreed to recommend that Inteliquent’s stockholders vote to adopt the definitive agreement. The transaction is subject to certain conditions, including approval from Inteliquent stockholders, the expiration or termination of the applicable waiting period under the Hart-Scott-Rodino Antitrust Improvements Act of 1976, as well as FCC and state regulatory approvals, approvals and other customary closing conditions. There is no financing condition associated with the proposed acquisition. Inteliquent expects to hold a special meeting of its stockholders to consider and act upon the transaction as promptly as practicable. The transaction is expected to close in the first half of 2017.
Under the terms of the agreement, for a period of 30 calendar days, Inteliquent may solicit alternative proposals from third parties. Inteliquent does not anticipate that it will disclose any developments with regard to this process unless and until the Inteliquent Board of Directors makes a decision with respect to a potential superior proposal. There are no guarantees that this process will result in a superior proposal.
Perella Weinberg Partners is acting as exclusive financial advisor to Inteliquent with Kirkland & Ellis LLP serving as legal counsel. Credit Suisse is acting as exclusive financial advisor to GTCR and Onvoy with Latham & Watkins LLP serving as legal counsel.
Inteliquent Third Quarter Earnings Results
In light of today’s transaction, Inteliquent has canceled its third quarter 2016 earnings conference call previously scheduled to take place on Thursday, November 3, 2016 at 10:00 am Eastern Time. Inteliquent will file its Form 10-Q for the third quarter of 2016 on or before November 9, 2016.
About Inteliquent
Inteliquent is a premier interconnection partner for communication service providers of all types. As the nation’s highest quality provider of voice and messaging interconnection services, Inteliquent is used by nearly all national and regional wireless carriers, cable companies, and CLECs in the markets it serves, and its network carries approximately 21 billion minutes of traffic per month. With the recent launch of its Omni IQsm solution, Inteliquent is now also fully dedicated to supporting the growing market of next generation service providers. For more information, please visit www.inteliquent.com.
About GTCR
Founded in 1980, GTCR is a leading private equity firm focused on investing in growth companies in the Financial Services & Technology, Healthcare, Technology, Media & Telecommunications and Growth Business Services industries. The Chicago-based firm pioneered The Leaders Strategy™ – finding and partnering with management leaders in core domains to identify, acquire and build market-leading companies through transformational acquisitions and organic growth. Since its inception, GTCR has invested more than $12 billion in over 200 companies. For more information, please visit www.gtcr.com.
About Onvoy
Onvoy is a leading Communications Enabler offering voice, messaging and mobility solutions supported by our nationwide carrier-grade network. Committed to empowering customers with the solutions they need to enable global communications across various applications in a continuously changing environment, Onvoy employs state of the art technology and provides customers control of their core communications infrastructure via carrier platforms and APIs. These interfaces allow customers to build, provision and support more innovative and integrated communication services. For more information, please visit www.onvoy.com.
Important Information and Where to Find It
In connection with the proposed merger contemplated by the Agreement and Plan of Merger, dated November 2, 2016, by and among Inteliquent, Onvoy Igloo Merger Sub, Inc. and Onvoy, LLC (the “Merger Agreement”), Inteliquent will file with the Securities and Exchange Commission (the “SEC”) and furnish to Inteliquent’s stockholders a definitive proxy statement. BEFORE MAKING ANY VOTING DECISION, INTELIQUENT’S STOCKHOLDERS ARE URGED TO READ THE DEFINITIVE PROXY STATEMENT CAREFULLY AND IN ITS ENTIRETY WHEN IT BECOMES AVAILABLE AND ANY OTHER DOCUMENTS TO BE FILED WITH THE SEC IN CONNECTION WITH THE PROPOSED MERGER OR INCORPORATED BY REFERENCE INTO THE DEFINITIVE PROXY STATEMENT (IF ANY) BECAUSE THEY WILL CONTAIN IMPORTANT INFORMATION ABOUT THE PROPOSED TRANSACTION AND THE PARTIES TO THE PROPOSED TRANSACTION. Investors and stockholders may obtain a free copy of documents filed by Inteliquent with the SEC at the SEC’s website at http://www.sec.gov. In addition, investors and stockholders may obtain a free copy of Inteliquent’s filings with the SEC at Inteliquent’s website at http://ir.inteliquent.com/sec.cfm or by directing a written request to: Inteliquent, Inc., 550 West Adams Street, Suite 900, Chicago, Illinois 60661, Attn: Investor Relations.
Inteliquent and certain of its directors, executive officers, and certain other members of management and employees of Inteliquent may be deemed to be participants in the solicitation of proxies from stockholders of Inteliquent in favor of the proposed merger. Information about directors and executive officers of Inteliquent is set forth in the proxy statement for Inteliquent’s 2016 annual meeting of stockholders, as filed with the SEC on Schedule 14A on April 8, 2016. Additional information regarding these individuals and other persons who may be deemed to be participants in the solicitation of proxies, as well as any direct or indirect interests they may have in the proposed merger, will be included in the definitive proxy statement with respect to the proposed merger Inteliquent will file with the SEC and furnish to Inteliquent’s stockholders.
Forward Looking Statements
Statements herein regarding the proposed transaction between Inteliquent, Onvoy, LLC and Onvoy Igloo Merger Sub, Inc., future financial and operating results, benefits and synergies of the transaction, future opportunities for the companies and any other statements about future expectations and the intent of any parties about future actions constitute “forward-looking statements” as defined in the federal securities laws. Forward-looking statements may be identified by words such as “believe,” “expects,” “anticipates,” “projects,” “intends,” “should,” “estimates” or similar expressions. Such statements are based upon current beliefs, expectations and assumptions and are subject to significant risks and uncertainties. There are a number of important factors that could cause actual results or events to differ materially from those indicated by such forward-looking statements, including: (1) conditions to the closing of the transaction may not be satisfied; (2) the transaction may involve unexpected costs, liabilities or delays; (3) the business of Inteliquent may suffer as a result of uncertainty surrounding the transaction; (4) the outcome of any legal proceedings related to the transaction; (5) Inteliquent may be adversely affected by other economic, business, and/or competitive factors; (6) the occurrence of any event, change or other circumstances that could give rise to the termination of the Merger Agreement; (7) the ability to recognize benefits of the transaction; (8) risks that the transaction disrupts current plans and operations and the potential difficulties in employee retention as a result of the transaction; and (9) other risks to consummation of the transaction, including the risk that the transaction will not be consummated within the expected time period or at all. If the transaction is consummated, stockholders unaffiliated with the transaction will cease to have any equity interest in Inteliquent and will have no right to participate in its earnings and future growth. Inteliquent, GTCR, and Onvoy believe these forward-looking statements are reasonable; however, undue reliance should not be placed on any forward-looking statements, which are based on current expectations. All written and oral forward-looking statements attributable to Inteliquent, GTCR, or Onvoy or persons acting on behalf of Inteliquent, GTCR, or Onvoy’s behalf are qualified in their entirety by these cautionary statements. Further, forward-looking statements speak only as of the date they are made, and Inteliquent, GTCR, and Onvoy undertake no obligation to update or revise forward-looking statements to reflect changed assumptions, the occurrence of unanticipated events or changes to future operating results over time unless required by law. Past financial or operating performance are not necessarily reliable indicators of future performance and you should not use our historical performance to anticipate results or future period trends.
Additional factors that may affect future results are contained in Inteliquent’s filings with the SEC, including its Annual Report on Form 10-K for the year ended December 31, 2015, which are available at the SEC’s website at http://www.sec.gov. The information set forth herein speaks only as of the date hereof, and any intention or obligation to update any forward-looking statements as a result of developments occurring after the date hereof is hereby disclaimed unless required by law.

CONTACT INFORMATION
For Inteliquent:
Investor Contact
Emily Naylor
investorrelations@inteliquent.com
For GTCR:
Eileen Rochford
eileenr@theharbingergroup.com
For Onvoy:
Marketing Director
Andi Cook
andi.cook@onvoy.com